Francisco José González González

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To assess the hypothesis that gap junctions (GJs) participate on leukocyte-endothelium interactions in the inflammatory response, we compared leukocyte adhesion and transmigration elicited by cytokine stimulation in the presence or absence of GJ blockers in the hamster cheek pouch and also in the cremaster muscle of wild-type (WT) and endothelium-specific(More)
Ventral spinal root avulsion causes complete denervation of muscles in the limb and also progressive death of segmental motoneurons (MN) leading to permanent paralysis. The chances for functional recovery after ventral root avulsion are very poor owing to the loss of avulsed neurons and the long distance that surviving neurons have to re-grow axons from the(More)
We studied the responses of 57 visual cells of the superior colliculus of the albino rat to bright sweeping and stationary flashing bright bars to determine the properties of their receptive fields. We observed that 9% (8% in superficial and 11% in deep layers) of the studied cells presented orientation preference and 16% showed direction selectivity (13%(More)
The dynamic regulation of blood flow in the peripheral circulation comprises multiple mechanisms that work in concert to provide adequate control of blood supply to the various vascular beds that feed organ systems. Blood vessels actively respond to different stimuli to adapt vessel diameter according to the continuously changing metabolic requirements of(More)
AMP-activated protein kinase (AMPK) in the ventromedial nucleus of the hypothalamus (VMH) and orexin (OX) in the lateral hypothalamic area (LHA) modulate brown adipose tissue (BAT) thermogenesis. However, whether these two molecular mechanisms act jointly or independently is unclear. Here, we show that the thermogenic effect of bone morphogenetic protein 8B(More)
INTRODUCTION Neuromuscular diseases cause a number of limitations which may be improved by using a telemedicine system. These include functional impairment and dependence associated with muscle weakness, the insidious development of respiratory failure and episodes of exacerbation. MATERIAL AND METHODS The present study involved three patients with severe(More)
OBJECTIVE To study the possible effect of oral sildenafil citrate on the response of cortical visual cells to visual stimulation. METHOD Multiunit activity was recorded from cortical area V2 of one behaving monkey. Spatio-temporal receptive field maps were obtained by using a reverse cross correlation technique and white noise visual stimulation before(More)