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BACKGROUND The purpose of this study was to evaluate the significance of the three-layered appearance of coronary arteries in adolescence and adults from intravascular ultrasound scans and to correlate these observations with histopathology. METHODS AND RESULTS Sixteen intact hearts were excised at autopsy from patients with no clinical history of(More)
Continuous estimation of cardiac output would be extremely useful for hemodynamic monitoring of patients in the operating room and intensive care settings. A recently developed echocardiographic imaging system provides real-time automated border detection (ABD) with the ability to measure cyclic changes in cavity area, and thus calculate changes in(More)
Triscupid annular motion is related to right ventricular systolic function in the same way mitral annulus motion is related to left ventricular function. Tricuspid annular excursion reflects the longitudinal motion of the right ventricle, and the systolic descent of the anulus correlates with systolic venous inflow to the right atrium. However, it has not(More)
BACKGROUND Accelerated coronary atherosclerosis is a major factor limiting allograft longevity in cardiac transplant recipients. Histopathology studies have demonstrated the insensitivity of coronary angiography for detecting early atheromatous disease in this patient population. Intracoronary ultrasound is a new imaging technique that provides(More)
BACKGROUND Coronary atherosclerosis has been demonstrated in young adults by postmortem pathology. Angiographic evaluation of coronary disease in young adults is limited by ethical issues and the insensitivity of angiography for detecting early pathology. Catheter-based intracoronary ultrasound has proven useful both in detecting and quantitating coronary(More)
BACKGROUND Transplant vasculopathy (TxCAD) limits longterm survival of allograft recipients. The possibility that preexistent donor coronary disease (PEDD) might accelerate this process is of concern. The serial progression of sites with and without PEDD as assessed by intravascular ultrasonic imaging is explored in this study. METHODS AND RESULTS Thirty(More)
OBJECTIVE To study the time course and underlying mechanisms of right heart filling after cardiac surgery. DESIGN A prospective observational study of adult patients undergoing cardiac surgery. SETTING Echocardiography laboratory of the Stanford University Medical Center. PATIENTS Twenty six patients (mean age 54.9) undergoing cardiac surgery were(More)
BACKGROUND Although intracoronary ultrasound (ICUS) has been validated for the early detection of transplant coronary artery disease (TxCAD), the prognostic importance of findings detected by this new imaging technique is unknown. METHODS AND RESULTS This study examined the relation of clinical outcome in 145 heart transplant recipients (mean age, 45.1(More)
Intravascular ultrasound, a new technique for real-time two-dimensional visualization of arteries and veins, delineates vessel wall morphology and measures luminal dimensions. This imaging method has been validated with in vitro systems and in peripheral vessels, but there are few in vivo coronary artery studies. Twenty cardiac transplant recipients with no(More)