Francisco Javier Ridruejo Perez

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Paradoxically, in eukaryotic cells, hydrogen peroxide (H(2)O(2)) accumulates in response to oxygen deprivation (hypoxia). The source of H(2)O(2) under hypoxia varies according to the species, organs, and tissue. In non-photosynthetic tissues, H(2)O(2) is mainly produced by activation of NAD(P)H-oxidases or by disruption of the mitochondrial electron(More)
It has been reported that dormancy-breaking compound hydrogen cyanamide (HC) stimulates the fermentative pathway and inhibits respiration in grapevine-buds, suggesting in this way, that a respiratory stress must be involved in the release of buds from dormancy. Here, we tested low-oxygen effect (hypoxia) on the bud-break response of endodormant grapevine(More)
In this paper we introduce TrGen, a traffic generation environment specifically designed to interact with simulators of interconnection networks for parallel and distributed systems. This environment is able to generate synthetic traffic, and actual traffic taken from traces (of previous program runs). It can also cooperate with complete-system simulators(More)
We discuss a collection of techniques, included in our INSEE simulation environment but applicable to other contexts, designed to do simulation-based performance studies of parallel computing systems using traces. We explain the mechanisms required to capture traces from MPI-based parallel applications, point out some important limitations in the way events(More)
Evaluation of high performance parallel systems is a delicate issue, due to the difficulty of generating workloads that represent, with fidelity, those that will run on actual systems. In this paper we make an overview of the most usual methodologies used to generate workloads for performance evaluation purposes, focusing on the network: random traffic,(More)
In this paper we show the difficulties encountered when performing full system simulation of a distributed memory parallel system. To illustrate the problem, we have chosen a workbench that evaluates the impact on application performance of some simple congestion-control mechanism that can be implemented in the interconnection network. Applications of(More)
Any simulation-based evaluation of an interconnection network proposal requires a good characterization of the workload. Synthetic traffic patterns based on independent traffic sources are commonly used to measure performance in terms of average latency and peak throughput. As they do not capture the level of self-throttling that occurs in most parallel(More)
BACKGROUND Pneumocystis without obvious accompanying pathology is occasionally reported in autopsied infant lungs. Its prevalence and significance are unknown. Interestingly, this mild infection induces a strong activation of mucus secretion-related genes in young immunocompetent rodents that has not been explored in infants. Excess mucus is induced by(More)