Francisco Javier Gonzalez

Learn More
BACKGROUND The filamentous fungus Trichoderma harzianum is used as biological control agent of several plant-pathogenic fungi. In order to study the genome of this fungus, a functional genomics project called "TrichoEST" was developed to give insights into genes involved in biological control activities using an approach based on the generation of expressed(More)
BACKGROUND The human pregnane X receptor (hPXR) is an orphan nuclear receptor that induces transcription of response elements present in steroid-inducible cytochrome P-450 gene promoters. This activation requires the participation of retinoid X receptors (RXRs), needed partners of hPXR to form heterodimers. We have investigated the expression of hPXR and(More)
Preamble Currently Spanish is the second native language in the world by number of speakers after the Mandarin Chinese. This second position means that the 6.7% of the world population is Spanish-speaking. The presence of the Spanish language in the world has not a direct correspondence with the number of research works related to the treatment of Spanish(More)
BACKGROUND Smokers undergoing surgery are at a higher risk of complications than non-smokers. Preoperative evaluation by an anesthesiologist could provide an excellent opportunity to promote smoking cessation. Previous surveys of anesthesiologists have found that self-reported smoking cessation counseling rates have room for improvement, but no study has(More)
Knowledge of the existence of filaggrin (FLG) gene mutations might be helpful for a subclassification of patients with atopic dermatitis (AD) which can be used to introduce individualized treatments. In this work the filaggrin content in the skin is assessed using Raman spectroscopy and the results are compared to FLG genotyping of Mexican-mestizo patients.(More)
In this work automatic methods for determining the number of gaussians per state in a set of Hidden Markov Models are studied. Four different mix-up criteria are proposed to decide how to increase the size of the states. These criteria, derived from Maximum Likelihood scores, are focused to increase the discrimination between states obtaining different(More)
  • 1