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The GI-101 human breast tumour xenograft line is unique in that it spontaneously metastasizes to the lungs of athymic murine hosts from subcutaneous trochar implants. Both tumour and lung metastases are positive for normal human breast tissue markers. GI-101 also is positive for the p53 antigen but negative for the c-erbB-2 oncogene.
This paper shows a rigorous approach based on algebraic specications and rewriting logic which makes up for the lack of current transformation languages and oers a balanced rigour-versus-intuition framework for model transformation, focusing on the MDA-QVT standards. To illustrate this approach, an example and some formal applications of these specications(More)
Resumen La propuesta MDA del OMG está teniendo un gran auge en los últimos años. A pesar de la numerosa documentación existente sobre ella, todavía existen aspectos no denidos, deni-dos de forma imprecisa o a los que todavía no se les ha prestado la suciente atención. Entre Sin embargo, si analizamos detenidamente la numerosa documentación existente(More)
We report a case of a 29-year-old male who presented with paraesthesia and skin lesions with excessive bleeding after skin biopsy leading to hematology consultation. He was found to have prolonged partial thromboplastin time (PTT) and monoclonal gammopathy on serum protein electrophoresis (SPEP). He experienced excessive bleeding leading to hospitalization(More)
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