Francisco Hernández

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Advances in computer technologies have enabled scientists to explore research issues in their respective domains at scales greater and finer than ever before. The availability of efficient data collection and analysis tools presents researchers with vast opportunities to process heterogeneous data within a distributed environment. To support the(More)
The oligosaccharides of the mucus glycoproteins of the human rectum are important for the lubricant and protective role suggested for the rectal mucus. Changes in oligosaccharide composition are observed in several colon diseases, and some of these changes could be used as diagnostic and prognostic indicators. Thus, a previous knowledge of the normal mucus(More)
Addressing the management challenges for a multitude of distributed cloud architectures, we focus on the three complementary cloud management problems of predictive elasticity, admission control, and placement (or scheduling) of virtual machines. As these problems are intrinsically intertwined we also propose an approach to optimize the overall system(More)
Lectin histochemistry is a useful method that allows the in situ identification of the terminal sugar moieties of the carbohydrates that form the glycoconjugates. Moreover, when it is combined with chemical or enzymatic deglycosylation pretreatments, lectin histochemistry can be employed to determine if carbohydrates are linked to the protein core by means(More)
Previous works have shown that glycoconjugates with terminal fucose (Fuc) are located in the primordial germ cells (PGCs) of some mammals and might play a role in the migration and adhesion processes during development. The aim of this work was to identify the terminal Fuc moieties of Xenopus PGCs by means of three Fuc-binding lectins: from asparagus pea(More)
As more Grid workflow applications are built, workflow sharing and reuse becomes important, because (i) building a Grid workflow application from scratch is still a challenging task for domain scientists, and (ii) reusing of established and validated workflows not only reduces workflow authoring time but also improves the quality of workflows. In this(More)
 Although the role of the blood group antigens in the gastrointestinal tract is not well understood, alterations in blood group-related antigens have been described in some pathological processes. Thus, the knowledge of their expression under normal conditions is of special interest. Those individuals expressing their ABO blood group in exocrine epithelia(More)
Glycoconjugates could play a role in cell adhesion and migration mechanisms, including the locomotive movements of the primordial germ cells (PGCs) during the development of the embryo. In the present work, we have studied by lectin histochemistry the presence of N-acetylgalactosamine (GalNAc) in the glycans of the Xenopus PGCs, as a first approach to(More)
The aim of the present work was to study the carbohydrate moieties present on N- and O-linked oligosaccharides of duct cells of a urodele amphibian testis, by means of lectin histochemistry. It was found that duct cells have a carbohydrate composition that includes ensuremath α(1,3)-, α(1,4)- or α(1,6)-linked Fuc and Man on N-linked oligosaccharides, Gal(More)
The origin of the acrosome is controversial, because of both its lysosomal nature and at the moment of its appearance, which seems to be species-specific. Considering the amazing organization shown by the acrosome of some urodele amphibians, HPA-colloidal gold cytochemistry was used to analyze the biogenesis of the acrosome in the urodele Pleurodeles waltl(More)