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PURPOSE Because the occurrence of postoperative myocardial ischaemia (MI) predicts subsequent cardiac morbidity and mortality, we determined the prevalence of and risk factors for MI in hip and knee arthroplasty patients. METHODS High-sensitivity cardiac troponin T (hs-cTnT) was measured on stored samples from postoperative day two in 394 hip and knee(More)
HIV1(+) smokers develop emphysema at an earlier age and with a higher incidence than HIV1(-) smokers. Since human alveolar macrophages (AMs) are capable of producing proteases that degrade extracellular matrix components, we hypothesized that up-regulation of AM matrix metalloproteinases may be associated with the emphysema of HIV1(+) smokers. Microarray(More)
Heterologous viruses may transactivate or suppress human immunodeficiency virus (HIV)-1 replication. An adenovirus type 5 gene transfer vector (Ad5) HIV-1 vaccine was recently evaluated in a clinical trial, without efficacy. In this context, it is relevant to ask what effect Ad vectors have on HIV-1 replication, particularly in cells that are part of the(More)
Wnt proteins that signal via the canonical Wnt/β-catenin pathway directly regulate osteoblast differentiation. In contrast, most studies of Wnt-related effects on osteoclasts involve indirect changes. While investigating bone mineral density loss in the setting of human immunodeficiency virus (HIV) infection and its treatment with the protease inhibitor(More)
thrombocytopenic purpura plasma-associated apoptosis endothelial cells, mediating their lineage-specific sensitivity to thrombotic and TRAIL modulate c-FLIP in γ Synergistic interactions between interferon-(2497 articles) Hemostasis, Thrombosis, and Vascular Biology Articles on similar topics can be found in the following Blood collections Information about(More)
Microvascular endothelial cell (MVEC) injury coupled to progression of platelet microthrombi facilitated by ADAMTS13 deficiency is characteristic of idiopathic and HIV-linked thrombotic thrombocytopenic purpura (TTP). Cytokines capable of inducing MVEC apoptosis in vitro are up-regulated in both TTP and HIV infection. However, the concentrations of these(More)
associated apoptosis − thrombotic thrombocytopenic purpura plasma c-FLIP in endothelial cells, mediating their lineage-specific sensitivity to and TRAIL modulate γ Synergistic interactions between interferon
We report a method to optically control the effective permittivity of a composite dielectric in which the active inclusions are fabricated from pulverized semi-insulating GaAs. The electric dipoles from the inclusions are controlled by photo-generation of charge carriers using infrared light. An infrared transparent binder provides the matrix material. Our(More)
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