Francisco Álvarez

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OBJECTIVE To establish the indications for surgical intervention, at the appropriate gestational duration, for brain tumors in pregnant women, and to evaluate any association pregnancy hormones may have with the rate of growth or development of complications of brain tumors. METHODS We observed seven women with brain tumors associated with pregnancy in a(More)
OBJECTIVE The aim of this study was to define the incidence of type 2 diabetes in a low-risk Caucasian population in northern Spain and its association with various risk factors. RESEARCH DESIGN AND METHODS The Asturias Study is a prospective, population-based survey of diabetes and cardiovascular risk factors. The baseline examination was carried out(More)
The aim of this study was to assess the presence of alcohol, illicit drugs and medicinal drugs among Spanish drivers involved in fatal road accidents between 1991 and 2000. Samples were obtained for 5745 drivers killed in road accidents from January 1991 to December 2000. Of the samples, 91.7% represented males and 8.3% females; 40.7% were under 30 years of(More)
BACKGROUND The aim of this study was to evaluated an alternative echocardiographic method to calculate mean pulmonary arterial pressure (MPAP). METHODS One hundred two patients were studied with simultaneous right-heart catheterization (RHC) and echocardiography. MPAP was calculated by adding the right ventricular-right atrial mean systolic gradient to(More)
Psychotropic medications are increasingly used for very young children. Patterns of use in a well-described group of children 3 years and younger with a diagnostic label of attention-deficit hyperactivity disorder (ADHD) reveal both reasons to use such medications and concerns about how these medications are used. Of 223 children with ADHD, more than half(More)
In a multicenter 1-year trial of contraceptive vaginal rings (rings) involving 150 women, three dose combinations of the progestin Nestorone (NES) and ethinylestradiol (EE) were compared with respect to effectiveness, safety and acceptability. Mean in vitro drug release rates for the three doses were 150 and 15, 150 and 20 and 200 and 15 microg/day of NES(More)
OBJECTIVE We examined the clinical performance of contraceptive vaginal rings (rings) delivering Nestorone (NES) progestin and ethinyl estradiol (EE). Ring removal times were signaled by menstrual events. Bleeding patterns, adverse events, patterns of use and continuation rates were the principal parameters evaluated. METHODS In a two-stage 6-month trial,(More)
A sample of 2,086 university students in Valladolid (Spain) were surveyed in 1994 to assess their current use of illicit drugs. That information was used as a baseline to show the trends in the last decade in order to compare two other studies carried out on a similar target population in 1984 and 1990. Of those surveyed, 28.3% had taken some illicit drug(More)
Regardless of the knowledge representation schema chosen to implement a linguistic resource, conceptual design is an important step in its development. However, it is normally put aside by developing efforts as they focus on content, implementation and time-saving issues rather than on the software engineering aspects of the construction of linguistic(More)
Identification of early mechanical complications (EMC) of central venous catheterizations (CVC) in pediatric patients and determination of EMC risk factors. Prospective observational study. Pediatric intensive-care unit in a university hospital. Eight-hundred and twenty-five CVC were performed in 546 patients. Age, weight, gender, mechanical ventilation,(More)