Francis X Graydon

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A visuo-motor sequence can be learned as a series of visuo-spatial cues or as a sequence of effector movements. Earlier imaging studies have revealed that a network of brain areas is activated in the course of motor sequence learning. However, these studies do not address the question of the type of representation being established at various stages of(More)
The unique ability to learn transformed or altered visuo-motor relationships during motor learning (visuo-motor transformation learning) has engaged researchers for over a century. Compared to other forms of motor learning (e.g., sequence learning), little is known about plasticity in the cortical and/or subcortical systems involved. We used fMRI to isolate(More)
Confinement and isolation have always confounded the extraordinary endeavor of human spaceflight. Psychosocial health is at the forefront in considering risk factors that imperil missions of 1- to 2-yr duration. Current crewmember selection metrics restricted to behavioral observation by definition observe rather than prevent performance degradation and are(More)
OBJECTIVE To determine regions of brain activation associated with menopausal hot flashes and sweating. DESIGN Controlled laboratory study. SETTING University medical center. PATIENT(S) Symptomatic postmenopausal women and asymptomatic eumenorrheic women. INTERVENTION(S) None. MAIN OUTCOME MEASURE(S) Brain activation measured by functional(More)
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