Francis J. Nagle

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Previous investigators have reported that oxygen consumption (VO2) continues to rise after the initial 2- to 3-min transient period of exercise when work exceeds approximately 60% of VO2 max. The purpose of this investigation was to examine the possible causes of this slow rise in VO2. Eighteen subjects exercised for 20 min at 65% and at 80% of VO2 max on(More)
Twenty young males, all active in middle-distance running, were studied between January 1968 and May 1974 for the purpose of gathering longitudinal data regarding Vo2 during treadmil running. Vo2 submax (measured during the last 2 min of a 6-min run at 202 m/min) and Vo2 max values (measured during a 5-8 min increasing-speed run to exhaustion) were(More)
This study was conducted to determine whether the pedaling frequency of cycling at a constant metabolic cost contributes to the pattern of fiber-type glycogen depletion. On 2 separate days, eight men cycled for 30 min at approximately 85% of individual aerobic capacity at pedaling frequencies of either 50 or 100 rev·min−1. Muscle biopsy samples (vastus(More)
One purpose of this study was to determine whether the half time of the oxygen consumption (VO2) response at the onset of exercise varies with work intensity. Fifteen subjects performed 5 min of bicycle ergometer exercise across a range of relative work loads with VO2 determined continuously via computer analysis. The results revealed that the half time of(More)
Experiments were performed to determine whether endurance time, mean arterial pressure, or heart rate was related to either muscle length or external torque production in humans during isometric knee extension. Eight men and nine women performed isometric knee extension to the endurance limit at each of three muscle lengths, determined by knee angles of 40(More)
A small portable accelerometer was developed to estimate the energy expenditure of daily activities. The accelerometer is reported to be an improvement over movement counters currently on the market. The oxygen requirement of 14 different activities was measured in 21 subjects while each wore the accelerometer on the waist. A movement counter (mercury(More)
The purpose of this study was to investigate the influence of the size of the active muscle mass on the cardiovascular response to static contraction. Twelve male subjects performed one-arm handgrip (HG), two-leg extension (LE), and a "dead-lift" maneuver (DL) in a randomly assigned order for 3 min at 30% of maximal voluntary contraction. O2 uptake (VO2),(More)
White high school girls (n = 120) and boys (n = 120) aged 14–17 years, selected from 9th, 10th, 11th and 12 grades of a northern, midwest U.S. high school performed running exercise on a motor driven treadmill for determinations of maximal O2 uptake ( $$\dot V$$ O2 max). The mean $$\dot V$$ O2 max for all age groups was 40.8±4.0 and 54.7±5.6 ml/kg·min−1 for(More)
The purpose of this investigation was to describe the dynamics of carnitine metabolism during an acute episode of exercise. Twenty-eight subjects (14 male; 14 female) exercised for 40 min on a bicycle ergometer at 55% of their maximal aerobic capacities. Blood samples were obtained at rest, 10, 20, 30, and 40 min of exercise, and 15-min postexercise. Muscle(More)
Chronic endurance exercise training has been associated with decreased levels of total cholesterol and increased HDL-cholesterol. To our knowledge rapid changes in cholesterol and HDL-cholesterol during acute exercise have not been described under controlled conditions. We studied 28 subjects (14 males and 14 females) during bicycle exercise for 40 min at a(More)