Francis F Arhin

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Oritavancin, a semisynthetic lipoglycopeptide with activity against gram-positive bacteria, has multiple mechanisms of action, including the inhibition of cell wall synthesis and the perturbation of the membrane potential. Approved guidelines for broth microdilution MIC assays with dalbavancin, another lipoglycopeptide, require inclusion of 0.002%(More)
A, Bentchouala C et al. Multidrug-resistant Salmonella enterica serotype Senftenberg isolates producing CTX-M b-lactamases from Constantine, Algeria. nucleotide sequence of the pCTX-M3 plasmid and its involvement in spread of the extended-spectrum b-lactamase gene bla CTX-M-3. Worldwide disseminated armA aminoglycoside resistance methylase gene is borne by(More)
The inhaled form of Bacillus anthracis infection may be fatal to humans. The current standard of care for inhalational anthrax postexposure prophylaxis is ciprofloxacin therapy twice daily for 60 days. The potent in vitro activity of oritavancin, a semisynthetic lipoglycopeptide, against B. anthracis (MIC against Ames strain, 0.015 microg/ml) prompted us to(More)
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