Francis B V Keane

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BACKGROUND Despite the frequency of open and laparoscopic herniorraphy the effect of the hernia and subsequent repair on testicular function is unknown. Our objective was to determine if there is an association between inguinal hernia and hernia repair on testicular function. STUDY DESIGN Thirty-seven men aged 18 to 70 years were enrolled in a prospective(More)
Angiogenesis is intimately related to the growth and progression of tumours and must be induced to facilitate growth beyond a minimum size. It has been implicated in the development of metastases and survival in breast carcinoma. VEGF is a cytokine that plays an important role in angiogenesis. Its expression is increased in solid tumours during induction of(More)
BACKGROUND Physical Education and School Sport (PESS) is an integral part of the school curriculum in Ireland. Historically the "Healthy Body, Healthy Mind" philosophy has promoted the inclusion of PESS alongside more cognitive school subjects. Research suggests that PESS can promote cognitive function and provide educational benefits. However, there is(More)
A neonatal presentation of Caroli's disease with severe cardiac and progressive renal pathology is described. The availability of small paediatric endoscopes ensured early diagnosis. Despite aggressive medical management, the baby died with severe bleeding complications before potentially life saving multiple organ transplantation could take place.
Though peritonitis is a significant problem in managing patients on continuous ambulatory peritoneal dialysis (CAPD), it is normally readily diagnosed and successfully treated. However, when peritonitis is resistant to standard intraperitoneal antibiotic therapy, an underlying intra-abdominal pathology may be present. Establishing or refuting such a(More)
Homozygous homocystinuria, the most common genetic disorder of transulphuration, is associated with elevated plasma concentrations of homocystine, homocysteine, multiple clinical abnormalities and life-threatening thromboembolism. Several instances of vascular aneurysms have also been documented. More recently, an association between premature occlusive(More)
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