Francesco Zumbo

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R ecent advances have raised the hope of effective pharmacological or non-pharmacological treatments of atrial fibrillation (AF), and of better understanding of the pathophysiological mechanisms involved in the initiation and persistence of the arrhythmia. Inflammatory changes in the atrial structure have been observed after cardiac surgery but also in(More)
OBJECTIVES We investigated the long-term efficacy of cryo ablation for treatment of atrial flutter. BACKGROUND To our knowledge, no study has assessed the long-term efficacy of cryo ablation by assessing both symptom and conduction recurrence. METHODS A total of 45 consecutive patients with symptomatic atrial flutter were ablated with a 7-F, 6-mm-tip,(More)
Introduction: At the present time, several techniques are used or are under investigation for atrial fibrillation (AF) therapy. Nowadays, no well-defined target for such therapies has been yet completely identified. Furthermore, AF is an arrhythmia with high rates of recurrences, both symptomatic and asymptotic. Thus the measure of therapy success rates not(More)
Background: Larger tipped cryothermal catheters may deliver efficacy and procedure benefits in the treatment of patients with atrial flutter. Objective: To compare 7 French 6 mm and 9 French 8 mm tip cryothermal catheters (Freezor®, Xtra or Freezor®, MAX, CryoCath Technologies Inc., Kirkland, Canada) in terms of acute and chronic efficacy, and procedure(More)
Background: Cardiac cryoablation has been used to successfully treat a variety of arrhythmias. Objective: This study documents our experience with a new 9 French (FR) 8 mm cryocatheter for ablation treatment of symptomatic atrial flutter. Methods: A total of 77 consecutive patients with symptomatic atrial flutter were treated. Electrophysiological studies(More)
We describe one case of myocardial ischemia due to a coronary-pulmonary fistula, successfully treated with coils. Coronary fistulae are a rare cause of angina in adults with normal coronary arteries. Percutaneous treatment represents an alternative to surgery and may be offered as a relatively low risk procedure. The choice between surgical and percutaneous(More)
Background: The study sought to evaluate whether electrogram-aided identification of hot spot targets produces additional clinical and/or procedure benefits when using a non-traditional focal cryo ablation method to treat common atrial flutter. Methods: A preliminary study identified a specific electrogram criterion (e.g., a stimulus to onset of electrogram(More)
In selected patients suffering from variant angina, an implantable cardioverter-defibrillator (ICD) and coronary stenting can be helpful to prevent sudden death and treat coronary artery spasm. We report a case of a 47-year-old woman suffering from variant angina, who experienced an episode of ventricular fibrillation promptly cardioverted. After coronary(More)
Objectives: The aims of this study were to compare the efficacy of a 2- versus a 3 RF lesions ablation procedure in the RA in patients with paroxysmal AF, and to map right atrial activation during AF. Background: RF catheter-mediated ablation lines mimicking the Maze operation have been proposed as a novel curative approach for AF. The relationship between(More)
Right atrial (RA) mapping has been recently more carefully examined in patients with idiopathic atrial fibrillation (AF) in order to improve radiofrequency (RF) catheter-mediated ablation lines to control recurrences. The aim of this study was to map right atrial activation during AF to analyze relationship between anatomy and atrial activation for specific(More)