Francesco Lodesani

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The α2 glycine receptor (GlyR) subunit, abundant in embryonic neurons, is replaced by α1 in the adult nervous system. The single-channel activity of homomeric α2 channels differs from that of α1-containing GlyRs, as even at the lowest glycine concentration (20 µM), openings occurred in long (>300-ms) groups with high open probability (P(open); 0.96;(More)
Ligand-gated ion channels electrical behaviour and, in particular, their conductance are influenced by the binding between receptive sites on channel surface and specific molecules. These channels, inserted in biomimetic membranes and in presence of a proper electronic system for acquiring and elaborating the electrical signal, could give us the possibility(More)
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