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Increased antagonist muscle co-activation, seen in motor-impaired individuals, is an attempt by the neuromuscular system to provide mechanical stability by stiffening joints. The aim of this study was to investigate the co-activation pattern of the antagonist muscles of the ankle and knee joints during walking in patients with cerebellar ataxia, a(More)
Our aim was to perform a comprehensive analysis of the global and segmental features of gait in patients with genetically confirmed inherited ataxias. Sixteen patients with autosomal dominant (spinocerebellar ataxia, SCA1 or 2) or recessive (Friedreich’s ataxia, FRDA) ataxia were studied. We used a motion analysis system to record gait kinematic and kinetic(More)
We present T` ıpalo, an algorithm and tool for automatically typing DBpedia entities. T` ıpalo identifies the most appropriate types for an entity by interpreting its natural language definition, which is extracted from its corresponding Wikipedia page abstract. Types are identified by means of a set of heuristics based on graph patterns, dis-ambiguated to(More)
A compact description of coordinated muscle activity is provided by the factorization of electromyographic (EMG) signals. With the use of this approach, it has consistently been shown that multimuscle activity during human locomotion can be accounted for by four to five modules, each one comprised of a basic pattern timed at a different phase of gait cycle(More)
FRED is a machine reading tool for converting text into internally well-connected and quality linked-data-ready ontologies in web-service-acceptable time. It implements a novel approach for ontology design from natural language sentences, combining Discourse Representation Theory (DRT), linguistic frame semantics, and Ontology Design Patterns (ODP). The(More)
We have implemented a novel approach for robust ontology design from natural language texts by combining Discourse Representation Theory (DRT), linguistic frame semantics, and ontology design patterns. We show that DRT-based frame detection is feasible by conducting a comparative evaluation of our approach and existing tools. Furthermore, we define a(More)
Several studies have demonstrated how cerebellar ataxia (CA) affects gait, resulting in deficits in multijoint coordination and stability. Nevertheless, how lesions of cerebellum influence the locomotor muscle pattern generation is still unclear. To better understand the effects of CA on locomotor output, here we investigated the idiosyncratic features of(More)
In adult guinea pigs, the oculomotor nerve was sectioned proximally (at the tentorial edge) or more distally (at the orbital fissure) and immediately repaired by reapproximation. During a 24-week postoperative period, extrinsic eye motility was assessed by analyzing the vestibulo-ocular reflexes. The regenerated oculomotor nerve was studied morphometrically(More)
To study oculomotor nerve regeneration in rats, the oculomotor nerve was approached microsurgically and was sectioned at the base of the skull. The nerve stumps were reapproximated and affixed with a plasma clot in Group I animals and were separated by a gap in Group II animals. Visceral eye motility was evaluated weekly between 1 day and 40 weeks after(More)
People with Parkinson's disease (PD) often have a posture characterized by lateral trunk flexion poorly responsive to antiparkinsonian drugs. To examine the effects of a rehabilitation programme (daily individual 90-minute-sessions, 5-days-a-week for 4-consecutive weeks) on lateral trunk flexion and mobility, 22 PD patients with mild to severe lateral trunk(More)