Francesco Bonetti

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L ymphangioleiomyomatosis (LAM) is a rare lung disease, which occurs sporadically or in association with the genetic disease tuberous sclerosis complex (TSC) [1, 2]. Patients with LAM usually develop progressive dyspnoea and recurrent pneumothorax, chylous collections and occasional haemoptysis [1]. Extra pulmonary lymphadenopathy and cystic masses of the(More)
The aim of the present work was to test the ability to predict the instant at which a grasping hand touches an object. Our hypothesis was that, because of the activation of the mirror-neuron system, the same predictive process necessary for action execution should be active during observation. Experimental evidence indicates, however, that not only observed(More)
OBJECTIVES The aim of this study was to investigate the principal discharge diagnosis and related comorbidity in hospitalized older patients affected by dementia. METHODS Data from 51,838 consecutive computerized discharge records of the St. Anna University Hospital (Ferrara, Italy) were analyzed. Records included only subjects aged ≥60 years. Number of(More)
Homocysteine (Hcy) is a key junction in methionine metabolism. In inherited forms of hyperhomocysteinemia patients develop early vascular damage and cognitive decline. Hyperhomocysteinemia is a common consequence of dietary, behavioral and pathological conditions and is epidemiologically related to different diseases, among them neurodegenerative ones are(More)
We prospectively assessed the frequency of pulmonary complications and the natural course of lung function after bone marrow transplantation (BMT), as well as the effect of several risk factors in a homogeneous group of 39 children who underwent allogeneic or autologous BMT for haematological malignancies between 1992 and 1995. Four patients developed(More)
Programmed cell death is an important determinant of the response to chemotherapy. Among the factors controlling this process, a significant role is played by bcl-2 and p53, the expression of which, together with estrogen receptor content and tumor proliferative activity, was investigated by means of immunohistochemistry in 55 advanced breast cancer(More)
BACKGROUND In central nervous system cholesterol cannot be degraded but is secreted into circulation predominantly in the form of its polar metabolite 24(S)-hydroxycholesterol (24S-OH-Chol). Some studies suggested an association between 24S-OH-Chol metabolism and different neurological diseases including dementia. A possible decrease in 24S-OH-Chol plasma(More)
Sir, We read with great interest the paper by Farshid et al (2008) recently published in the Br J Cancer. The authors address a complex problem that is the daily experience of professionals involved in breast cancer screening programmes worldwide. In fact, although radiologically suspicious lesions have well-recognised guidelines intended to determine the(More)
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