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Circulating nerve growth factor levels are increased in humans with allergic diseases and asthma.

• Alessandro Lambiase, Sergio Bonini, Francesco Angelucci, Leonardo Magrini, Luigi Manni, Luigi Aloe
• Proceedings of the National Academy of Sciences…
• 1996

Nerve growth factor (NGF) serum levels were measured in 49 patients with asthma and/or rhinoconjunctivitis and/or urticaria-angioedema. Clinical and biochemical parameters, such as bronchial… (More)

BDNF in schizophrenia, depression and corresponding animal models

• Francesco Angelucci, Stefan Brene, Aleksander A. Mathé
• Molecular Psychiatry
• 2005

Understanding the etiology and pathogenesis schizophrenia and depression is a major challenge facing psychiatry. One hypothesis is that these disorders are secondary to a malfunction of neurotrophic… (More)

Lithium treatment alters brain concentrations of nerve growth factor, brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor in a rat model of depression.

• Francesco Angelucci, Luigi Aloe, Patricia A Jiménez-Vasquez, Aleksander A. Mathé
• The international journal of…
• 2003

Nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF) and glial cell line-derived neurotrophic factor (GDNF) are proteins involved in neuronal survival and plasticity of dopaminergic,… (More)

pSTAT1, pSTAT3, and T-bet expression in peripheral blood mononuclear cells from relapsing-remitting multiple sclerosis patients correlates with disease activity.

• Giovanni Frisullo, Francesco Angelucci, +7 authors Anna Paola Batocchi
• Journal of neuroscience research
• 2006

Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system, and it is considered to be a T helper 1 (Th1) cell-mediated autoimmune disease. T-bet has been… (More)

Brain-derived neurotrophic factor and tyrosine kinase receptor TrkB in rat brain are significantly altered after haloperidol and risperidone administration.

• Francesco Angelucci, Aleksander A. Mathé, Luigi Aloe
• Journal of neuroscience research
• 2000

The antipsychotics haloperidol and risperidone are widely used in the therapy of schizophrenia. The former drug mainly acts on the dopamine (DA) D(2) receptor whereas risperidone binds to both DA and… (More)

Mapping the differences in the brain concentration of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) in an animal model of depression.

• Francesco Angelucci, Luigi Aloe, Patricia A Jiménez Vasquez, Aleksander A. Mathé
• Neuroreport
• 2000

Antidepressant drugs as well as electroconvulsive stimuli can significantly influence brain concentrations of neurotrophic factors. However, it is not known whether the baseline brain concentrations… (More)

A single intraperitoneal injection of endotoxin in rats induces long-lasting modifications in behavior and brain protein levels of TNF-α and IL-18

• Paola Bossù, Debora Cutuli, +7 authors Laura Petrosini
• Journal of Neuroinflammation
• 2011

Systemic inflammation might cause neuronal damage and sustain neurodegenerative diseases and behavior impairment, with the participation of pro-inflammatory cytokines, like tumor necrosis factor… (More)

Inhibition of Schistosoma mansoni thioredoxin-glutathione reductase by auranofin: structural and kinetic aspects.

• Francesco Angelucci, Ahmed Amir Radwan Sayed, +6 authors Andrea Bellelli
• The Journal of biological chemistry
• 2009

Schistosomiasis is a parasitic disease affecting over 200 million people currently treated with one drug, praziquantel. A possible drug target is the seleno-protein thioredoxin-glutathione reductase… (More)

Chronic amphetamine treatment reduces NGF and BDNF in the rat brain

• Francesco Angelucci, Susanne H. M. Gruber, Aram El Khoury, Pietro A. Tonali, Aleksander A. Mathé
• European Neuropsychopharmacology
• 2007

Amphetamines (methamphetamine and d-amphetamine) are dopaminergic and noradrenergic agonists and are highly addictive drugs with neurotoxic effect on the brain. In human subjects, it has also been… (More)

Chronic parasite infection in mice induces brain granulomas and differentially alters brain nerve growth factor levels and thermal responses in paws

• Luigi Aloe, Rolando Moroni, Marco Fiore, Francesco Angelucci
• Acta Neuropathologica
• 1996

Schistosoma mansoni infection, both in humans and in animal models, is known to induce granulomas in the liver and intestine. It has also been reported that in humans the eggs of this parasite can… (More)

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