Francesca Puppo

Learn More
Generation of skeletal muscles with forms adapted to their function is essential for normal movement. Muscle shape is patterned by the coordinated polarity of collectively migrating myoblasts. Constitutive inactivation of the protocadherin gene Fat1 uncoupled individual myoblast polarity within chains, altering the shape of selective groups of muscles in(More)
—In this paper we propose CMOS-compatible Memristive-Biosensors as label-free, highly sensitive sensors for in-air detection of Vascular Endothelial Growth Factor (VEGF) molecules. The memristive behavior of the fabricated devices is strongly affected by molecules in proximity of the wire surface. In this paper, we demonstrate the reproducibility of the(More)
— Integration of nanowire structures in more complex platforms combining microfluidics and multiplexing aspects may complex the electrical readout process. In the present work, fabrication of Aluminium (Al) lines for electrical connections is attempted followed by their integration to nanofabricated Memristive Biosensors that target at the label-free(More)
The main form of Facio-Scapulo-Humeral muscular Dystrophy is linked to copy number reduction of the 4q D4Z4 macrosatellite (FSHD1). In 5 % of cases, FSHD phenotype appears in the absence of D4Z4 reduction (FSHD2). In 70-80 % of these patients, variants of the SMCHD1 gene segregate with 4qA haplotypes and D4Z4 hypomethylation. We report a family presenting(More)
  • 1