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MiR-492 impairs the angiogenic potential of endothelial cells
- Francesca Patella, E. Leucci, +7 authors G. Rainaldi
- Biology, Medicine
- Journal of cellular and molecular medicine
- 26 June 2013
Endothelial cells growing in high glucose‐containing medium show reduced cell proliferation and in vitro angiogenesis. Evidence suggests that the molecular pathways leading to these cellular… Expand
The zebrafish/tumor xenograft angiogenesis assay as a tool for screening anti-angiogenic miRNAs
The zebrafish/tumor xenograft angiogenesis assay is used to approach tumor angiogenesis, a pivotal step in cancer progression and target for anti-tumor therapies. Here, we evaluated whether the assay… Expand
MicroRNAs mediate metabolic stresses and angiogenesis
MicroRNAs are short endogenous RNA molecules that are able to regulate (mainly inhibiting) gene expression at the post-transcriptional level. The MicroRNA expression profile is cell-specific, but it… Expand
The RNA activator ds-p21 potentiates the cytotoxicity induced by fludarabine in Dohh2 cells.
- Francesca Patella, Serena Lucotti, M. Rizzo, M. Evangelista, G. Rainaldi
- Biology, Medicine
- 17 February 2011
Recently, it has been reported that, in several tumor cell lines, short double-stranded RNAs tailored for promoter regions of specific genes are able to activate their transcription. Such molecules… Expand
Endothelial cell-derived nidogen-1 inhibits migration of SK-BR-3 breast cancer cells
BackgroundThe tumour microenvironment is a critical regulator of malignant cancer progression. While endothelial cells have been widely studied in the context of tumour angiogenesis, their role as… Expand
miR-492 inhibits the angiogenesis in zebrafish (Danio rerio) model
90PDual role of endothelial cell signaling in cancer progression
NIDOGEN1 as a novel regulator of endothelial control over breast cancer invasion and metastasis.
e23005Background: The microenvironment is a central regulator of cancer biology. While the contribution of fibroblasts has been largely studied, the role of endothelial cells as regulators of cancer… Expand
Endothelial cell derived micro-vesicular proteins to induce breast cancer cell migration.
e22014 Background: The microenvironment is a central regulator of tumor biology. While the contribution of fibroblasts has been largely studied, the role of endothelial cells as regulators of cance...