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MiR-492 impairs the angiogenic potential of endothelial cells
Endothelial cells growing in high glucose‐containing medium show reduced cell proliferation and in vitro angiogenesis. Evidence suggests that the molecular pathways leading to these cellularExpand
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The zebrafish/tumor xenograft angiogenesis assay as a tool for screening anti-angiogenic miRNAs
The zebrafish/tumor xenograft angiogenesis assay is used to approach tumor angiogenesis, a pivotal step in cancer progression and target for anti-tumor therapies. Here, we evaluated whether the assayExpand
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MicroRNAs mediate metabolic stresses and angiogenesis
MicroRNAs are short endogenous RNA molecules that are able to regulate (mainly inhibiting) gene expression at the post-transcriptional level. The MicroRNA expression profile is cell-specific, but itExpand
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The RNA activator ds-p21 potentiates the cytotoxicity induced by fludarabine in Dohh2 cells.
Recently, it has been reported that, in several tumor cell lines, short double-stranded RNAs tailored for promoter regions of specific genes are able to activate their transcription. Such moleculesExpand
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Endothelial cell-derived nidogen-1 inhibits migration of SK-BR-3 breast cancer cells
BackgroundThe tumour microenvironment is a critical regulator of malignant cancer progression. While endothelial cells have been widely studied in the context of tumour angiogenesis, their role asExpand
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NIDOGEN1 as a novel regulator of endothelial control over breast cancer invasion and metastasis.
e23005Background: The microenvironment is a central regulator of cancer biology. While the contribution of fibroblasts has been largely studied, the role of endothelial cells as regulators of cancerExpand
Endothelial cell derived micro-vesicular proteins to induce breast cancer cell migration.
e22014 Background: The microenvironment is a central regulator of tumor biology. While the contribution of fibroblasts has been largely studied, the role of endothelial cells as regulators of cance...