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- Francesca Di Sole, Komal Vadnagara, Orson W Moe, Victor Babich
- American journal of physiology. Renal physiology
- 2012
The calcineurin homologous protein (CHP) belongs to an evolutionarily conserved Ca(2+)-binding protein subfamily. The CHP subfamily is composed of CHP1, CHP2, and CHP3, which in vertebrates share… (More)
- Maria Favia, Lorenzo Guerra, +9 authors Valeria Casavola
- Molecular biology of the cell
- 2010
We have demonstrated that Na(+)/H(+) exchanger regulatory factor 1 (NHERF1) overexpression in CFBE41o- cells induces a significant redistribution of F508del cystic fibrosis transmembrane conductance… (More)
- Francesca Di Sole, Robert Cerull, Soeren Petzke, Valeria Casavola, Gerhard Burckhardt, Corinna Helmle-Kolb
- Journal of the American Society of Nephrology…
- 2003
Regulation of renal apical Na+/H+ exchanger 3 (NHE3) activity by adenosine has been suggested to contribute to acute control of mammalian Na(+) homeostasis. The mechanism by which adenosine controls… (More)
- Francesca Di Sole, Victor Babich, Orson W Moe
- Journal of the American Society of Nephrology…
- 2009
The Na(+)/H(+)-exchanger 3 (NHE3) is essential for regulation of Na(+) transport in the renal and intestinal epithelium. Although changes in cell surface abundance control NHE3 function, the… (More)
- Gerhard Burckhardt, Francesca Di Sole, Corinna Helmle-Kolb
- Journal of nephrology
- 2002
Na+/H+ exchangers (NHEs) extrude protons from, and take up sodium ions into cells. Six isoforms, NHE-1 - NHE-6, have been cloned. NHE proteins are composed of an N-terminal domain, which most likely… (More)
- Michael R. Wiederkehr, Francesca Di Sole, +5 authors Orson W Moe
- Kidney international
- 2001
BACKGROUND
Dopamine (DA) is a principal natriuretic hormone that defends extracellular fluid volume from a Na load. Natriuresis is effected partly through inhibiting the proximal tubule Na/H… (More)
- Francesca Di Sole, Lorenzo Guerra, +4 authors Valeria Casavola
- Experimental nephrology
- 2001
The opioid receptor antagonist, naloxone, has been shown to have beneficial effects in the kidney and to be implicated in renal salt and water balance. In the present study the signal transduction… (More)
- Ion Alexandru Bobulescu, Francesca Di Sole, Orson W Moe
- Current opinion in nephrology and hypertension
- 2005
PURPOSE OF REVIEW
Na/H exchangers (NHEs) are ubiquitous proteins with a very wide array of physiological functions, and they are summarized in this paper in view of the most recent advances.… (More)
- Francesca Di Sole, Robert Cerull, +7 authors Orson W Moe
- The Journal of biological chemistry
- 2004
Adenosine is an autacoid that regulates renal Na(+) transport. Activation of adenosine A(1) receptor (A(1)R) by N(6)-cyclopentidyladenosine (CPA) inhibits the Na(+)/H(+) exchanger 3 (NHE3) via… (More)
- Ion Alexandru Bobulescu, Henry Quiñones, +8 authors Orson W Moe
- American journal of physiology. Renal physiology
- 2010
Nephrogenic dopamine is a potent natriuretic paracrine/autocrine hormone that is central for mammalian sodium homeostasis. In the renal proximal tubule, dopamine induces natriuresis partly via… (More)