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  • Francesca Ceccherini-Silberstein, Valentina Svicher, +11 authors Carlo Federico Perno
  • Biology, Medicine
  • Journal of virology
  • 2007 (First Published: 15 October 2007)
  • Resistance to antivirals is a complex and dynamic phenomenon that involves more mutations than are currently known. Here, we characterize 10 additional mutations (L74V, K101Q, I135M/T, V179I, H221Y,Continue Reading
  • Valentina Svicher, Tobias Sing, +11 authors Carlo Federico Perno
  • Biology, Medicine
  • Journal of virology
  • 2006 (First Published: 15 July 2006)
  • We characterized 16 additional mutations in human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) whose role in drug resistance is still unknown by analyzing 1,906 plasma-derivedContinue Reading
  • Francesca Ceccherini-Silberstein, Kurt Van Baelen, +14 authors Carlo Federico Perno
  • Biology, Medicine
  • Antimicrobial agents and chemotherapy
  • 2010 (First Published: 1 September 2010)
  • The goal of this study was to explore the presence of integrase strand transfer inhibitor (InSTI) resistance mutations in HIV-1 quasispecies present in InSTI-naïve patients and to evaluate their inContinue Reading
  • Valentina Svicher, Francesca Ceccherini-Silberstein, +8 authors Carlo Federico Perno
  • Biology, Medicine
  • Antimicrobial agents and chemotherapy
  • 2005 (First Published: 1 May 2005)
  • Plasma-derived sequences of human immunodeficiency virus type 1 (HIV-1) protease from 1,162 patients (457 drug-naive patients and 705 patients receiving protease inhibitor [PI]-containingContinue Reading
  • Tomas Doyle, David T Dunn, +13 authors Bonaventura Clotet
  • Biology, Medicine
  • The Journal of antimicrobial chemotherapy
  • 2015 (First Published: 1 November 2015)
  • OBJECTIVES The aim of this study was to characterize the prevalence and patterns of genotypic integrase inhibitor (INI) resistance in relation to HIV-1 clade. METHODS The cohort comprised 533Continue Reading