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  • Uwe Fuhr, Gert R. Strobl, +7 authors Francisca Sanz
  • Chemistry, Medicine
  • Molecular pharmacology
  • 1993 (First Publication: 1 February 1993)
  • The inhibitory effect of 44 quinolone antibacterials and derivatives (common structure, 4-oxoquinoline-3-carboxylic acid) on cytochrome P450 isoform CYP1A2 activity was tested using human liverContinue Reading
  • M A Honrubia, Jorge Rodríguez, +9 authors Maria Isabel Loza
  • Chemistry, Medicine
  • Chemical & pharmaceutical bulletin
  • 1997
  • Cyproheptadine is a drug that shows high affinity for type 2 (5-HT2) receptors. We studied a series of compounds obtained by modification of the tricyclic system of Cyp (dibenzocycloheptadiene): 2fContinue Reading
  • Maria Isabel Loza, Teresa García Ferreiro, +7 authors Isabel Cadavid
  • Medicine, Chemistry
  • Journal of pharmaceutical sciences
  • 1993 (First Publication: 1 May 1993)
  • The antiserotoninergic activity at the serotonin receptor subtype 2 (5-HT2) of seven new 2-aminoethylbenzocyclanones was determined with respect to serotonin-induced contractions in rat aorta andContinue Reading
  • Ferran Sanz, Francesc Manaut, Jesús Rodríguez, Estrella Lozoya, Elena López-de-Briñas
  • Computer Science, Medicine
  • J. Comput. Aided Mol. Des.
  • 1993 (First Publication: 1 June 1993)
  • SummaryMEPSIM is a computational system which allows an integrated computation, analysis, and comparison of molecular electrostatic potential (MEP) distributions. It includes several modules. ModuleContinue Reading