Frances Rauscher

Learn More
In an effort at replication of the original report (Rosenthal and Bigelow, 1972) of increased callosal thickness in schizophrenic brains, the corpus callosum was measured in a blind study of 64 brains autopsied between the years 1972 and 1976. Diagnosis was established by independent chart review. The mean corpus callosum mid sections of 21 early onset(More)
A number of investigators have observed low platelet monoamine oxidase (MAO) activity in alcoholism. There is also preliminary evidence suggesting that low enzyme activity is principally associated with one of two putative subtypes of alcohol dependence, i.e., type II (male limited). The results of this study are consistent with two previous reports of(More)
Serotonin reuptake inhibitors (SSRI), such as venalafaxine and paroxetine, are used in the treatment of generalized anxiety disorder (GAD). Patients with GAD frequently have comorbid psychiatric disorders, such as depression. SSRIs are effective in the treatment of a variety of anxiety disorders and depression. Citalopram, a newer SSRI used in the treatment(More)
In an effort to establish correlations between abnormal behaviors characteristic of schizophrenia and simultaneous cerebral electrical activity, EEGs and electro-oculograms (EOGs) were continuously recorded for 2 to 24 hours by radiotelemetry from 40 patients with schizophrenia and 12 normal control subjects. Trained observers recorded specific behavior(More)
A diminished cutaneous response to intradermal histamine has been reported by schizophrenics in at least 12 studies over the past 50 years. This literature is reviewed and compared to the present investigation in which both the wheal and flare response to intradermal histamine is examined in chronic schizophrenic patients, their parents, and a healthy(More)
According to the dopamine (DA) hypothesis of schizophrenia, there is a functional excess of dopaminergic activity within unspecified areas of the brain in schizophrenic patients. As a clinical test of this hypothesis, we administered metyrosine for three weeks to symptomatic chronic male schizophrenic patients who were maintained on suboptimal doses of(More)
The benefits and side effects of electroconvulsive therapy (ECT) given two vs. three times per week were examined in depressed inpatients. Twenty subjects were randomly assigned to one of two treatment conditions (unilateral ECT two or three times weekly). Examiners without knowledge of treatment condition rated depression and psychiatric status and(More)
As a followup to a post-mortem study of the brains of schizophrenic and control subjects where the corpus callosum was found to be significantly thicker anteriorly in early onset compared to late onset schizophrenia, histological sections of 18 schizophrenic, 7 manic-depressive, and 11 medical/surgical control subjects were prepared using a stain for glia(More)
Previous studies on "craving" for alcohol after exposure to olfactory stimuli for alcohol may be criticized on the grounds that the control stimuli were not really appropriate. We included exposure to a preferred nonalcoholic beverage and to a sweet food item as additional control stimuli in order to better compare the salivary, autonomic, and self-reported(More)
/r has been demonstrated that humanists are far more Ukely to use filled pauses ("uh," "ah," or "um") during their lectures than are social or natural scientists This finding has been interpreted in terms of the hypothesis that filled pauses mdicate time out while the speaker searches for the next word or phrase Based on the assumption that the more options(More)