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The cardiac troponin C (cTnC) mutation, L29Q, has been found in a patient with familial hypertrophic cardiomyopathy. We previously showed that L29, together with neighboring residues, Asp2, Val28,… Expand
The Ca2+ sensitivity of force generation in trout cardiac myocytes is significantly greater than that from mammalian hearts. One mechanism that we have suggested to be responsible, at least in part,… Expand
[PDF] [Full Text] [Abstract] , December 19, 2007; 32 (1): 16-27. Physiol. Genomics Todd E. Gillis, Christian R. Marshall and Glen F. Tibbits Functional and evolutionary relationships of troponin C… Expand
Cardiac troponin C (cTnC) is a highly conserved ca2+ binding protein that plays an essential role in cardiomyocyte contraction. Sequence differences between cTnC homologs have been shown to be… Expand