François Philippe

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Authors/Task Force Members: Don Poldermans; (Chairperson) (The Netherlands)*; Jeroen J. Bax (The Netherlands); Eric Boersma (The Netherlands); Stefan De Hert (The Netherlands); Erik Eeckhout (Switzerland); Gerry Fowkes (UK); Bulent Gorenek (Turkey); Michael G. Hennerici (Germany); Bernard Iung (France); Malte Kelm (Germany); Keld Per Kjeldsen (Denmark);(More)
Authors/Task Force Members: Don Poldermans; (Chairperson) (The Netherlands)*; Jeroen J. Bax (The Netherlands); Eric Boersma (The Netherlands); Stefan De Hert (The Netherlands); Erik Eeckhout (Switzerland); Gerry Fowkes (UK); Bulent Gorenek (Turkey); Michael G. Hennerici (Germany); Bernard Iung (France); Malte Kelm (Germany); Keld Per Kjeldsen (Denmark);(More)
BACKGROUND The pathogenesis of unstable angina and non-Q-wave myocardial infarction is still poorly understood, and early evaluation of prognosis remains difficult. We therefore studied the predictive value of 5 biological indicators of inflammation, thrombogenesis, vasoconstriction, and myocardial necrosis, and we examined the effects of enoxaparin and(More)
  • F Philippe
  • Annales de cardiologie et d'angéiologie
  • 2004
In 2003, risk stratification in coronary heart disease is routinely performed by the results of coronary angiogram, the invasive gold standard angiography. Combined with the left ventricular ejection fraction assessment, the classification in one, two or three vessel disease remain the cornerstone of the revascularization strategy despite well-known(More)
OBJECTIVES We tested the hypothesis that different anticoagulant treatments may produce different platelet effects and von Willebrand factor (vWf) release in unstable angina. BACKGROUND The early increase of vWf has been reported to be a risk factor for adverse outcome in unstable angina. Anticoagulant drugs play a key role in stabilization of unstable(More)
Homocysteine is a graded risk factor for the incidence of stroke and for the degree of carotid atherosclerosis. Homocysteine is also a graded risk factor for the incidence of myocardial infarction but we do not know its precise relations to the severity of atherosclerosis in coronary patients. Seventy five symptomatic coronary patients were recruited for(More)
Long-term administration of prostacyclin (PGI2) improves the hemodynamic state, symptoms, and survival in patients with primary pulmonary hypertension, but it increases mortality in patients with heart failure despite obvious hemodynamic benefits when it is given acutely. We evaluated the mechanisms of action of PGI2 in patients with heart failure and(More)
Objectives. Robotic surgery enables to perform coronary surgery totally endoscopically. This report describes our experience using the da Vinci system for coronary artery bypass surgery. Methods. Patients requiring single-or-double vessel revascularization were eligible. The procedure was performed without cardiopulmonary bypass on a beating heart. Results.(More)
BACKGROUND Coronary artery bypass grafting with cardioplegia in patients with a low ejection fraction carries a risk of myocardial ischemia. Beating heart surgery is associated with hemodynamic changes when the heart is manipulated. We assessed an alternative: minimal extracorporeal circulation for coronary artery bypass grafting on a beating heart in(More)
AIMS To evaluate the safety and long-term efficacy of a true dedicated bifurcation bare metal stent (DBS) for the treatment of bifurcation coronary artery lesions. METHODS AND RESULTS Thirty-four patients were enrolled in this prospective multicentre study. The majority of culprit lesions were located on the left anterior descending artery/diagonal(More)