François Maurice

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Expression of bone proteins resulting from transdifferentiation of vascular smooth muscle cells into osteoblasts suggests that vascular calcifications are a bioactive process. Regulating molecules such as osteoprotegerin (OPG) and receptor activator of NF-kappaB ligand (RANKL) could play a key role in bone-vascular calcification imbalance. This study(More)
Two experiments were conducted on Préalpes ewes to test 2 complementary hypotheses which may explain the short lifespan of corpora lutea observed in some cases after ram-induced ovulation: i) the possible role of the uterus was tested by determining the effects of hysterectomy on the duration of luteal phases after the ram effect (RE); ii) the possible(More)
Experiments were designed to localize the central sites of action of melatonin involved in the control of seasonal reproduction. Ewes were exposed to long days and received microimplants of melatonin in the preoptic area (n = 9), anterior hypothalamus (n = 4), dorsolateral hypothalamus (n = 4), or mediobasal hypothalamus (n = 12). The effects of implants(More)
BACKGROUND Little is known on outcomes after transition to adult care among adolescents with perinatal HIV infection. Though there is data from other chronic pediatric diseases suggesting increased morbidity and mortality following transfer to adult care, this has not well been studied among the first wave of survivors of perinatal HIV infection. The(More)
The pineal hormone, melatonin, transduces photoperiodic information to the neuroendocrine axis of seasonally breeding mammals to regulate reproduction. It is not known where or how melatonin achieves this effect, but the recent identification of the pars tuberalis (PT) as the area with the highest density of melatonin binding sites suggests that this(More)
An experiment was designed to determine whether the pars tuberalis is the site of action of melatonin involved in the photoperiodic control of LH and prolactin secretion in sheep. In an attempt to produce a 'short-day' effect on these hormones (i.e. stimulation of LH secretion and inhibition of prolactin release), microimplants of melatonin were placed(More)
BACKGROUND Inflammation and malnutrition are recognized as important risk factors for cardiovascular disease (CVD) in hemodialysis (HD) patients. Owing to substantial short-term variability of serum C-reactive protein (CRP), more reliable markers of malnutrition-inflammation complex syndrome should be sought with stronger associations with the risk of CVD(More)
Formaldehyde (F) elicits contact dermatitis and asthma in subjects who are exposed to this chemical when it is applied on the skin or inhaled. An immediate-type hypersensitivity reaction was never confirmed in these reactions. F is widely used in hemodialysis to sterilize adhesives, surgical devices, or reconditioned dialyzers. A 20-year-old woman who was(More)
BACKGROUND Cardiac Troponin I (cTnI) levels are considered an important diagnostic tool in acute coronary events. They could be of predictive value in haemodialysis (HD) patients. However, the relationship between cTnI and the HD-induced inflammatory state remains unclear. The aim of this study was to explore the prognostic relevance to all-cause and(More)