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BACKGROUND The Global Registry of Acute Coronary Event (GRACE) risk score was developed in a large multinational registry to predict in-hospital mortality across the broad spectrum of acute coronary syndromes (ACS). Because of the substantial regional variation and temporal changes in patient characteristics and management patterns, we sought to validate(More)
ManyEars is an open framework for microphone array-based audio processing. It consists of a sound source localization, tracking and separation system that can provide an enhanced speaker signal for improved speech and sound recognition in real-world settings. ManyEars software framework is composed of a portable and modular C library, along with a graphical(More)
BACKGROUND Quality of life (QoL) is an important end point in heart failure (HF) studies. The Minnesota Living with Heart Failure questionnaire (MLHFQ) is the instrument most widely used to evaluate QoL in Heart Failure (HF) patients. It is a questionnaire containing 21 questions with scores ranging from 0 to 105. A best cut-off value for MLHFQ scores to(More)
Localization of sound sources in adverse environments is an important challenge in robot audition. The target sound source is often corrupted by coherent broadband noise, which introduces localization ambiguities as noise is often mistaken as the target source. To discriminate the time difference of arrival (TDOA) parameters of the target source and noise,(More)
BACKGROUND Although an early invasive approach has become standard strategy for the management of non-ST-segment elevation myocardial infarction (NSTEMI), the frequency and timing in Canada is uncertain. METHODS We examined the use and timing of coronary angiography, revascularization, and cardiovascular outcomes of NSTEMI patients: (1) admitted on(More)
BACKGROUND The question of whether gender-related disparities still exist in the treatment and outcomes of patients presenting with acute coronary syndromes (ACS) remains controversial. Using data from 4 registries spanning a decade, we sought to determine whether sex-related differences have persisted over time and to examine the treating physician's(More)
BACKGROUND Current guidelines support an early invasive strategy in the management of high-risk non-ST elevation acute coronary syndromes (NSTE-ACS). Although studies in the 1990s suggested that highrisk patients received less aggressive treatment, there are limited data on the contemporary management patterns of NSTE-ACS in Canada. OBJECTIVE To examine(More)
BACKGROUND We examine the clinical characteristics and outcomes of ST-elevation myocardial infarction (STEMI) patients receiving various reperfusion therapies in 2 contemporary Canadian registries. METHODS Of 4045 STEMI patients, 2024 received reperfusion therapy and had complete data on invasive management. They were stratified by reperfusion strategy(More)
BACKGROUND In-hospital assessment of left ventricular ejection fraction (LVEF) in non-ST-segment elevation acute coronary syndrome (NSTE-ACS) is emphasized in current practice guidelines. There are limited data regarding the evaluation of LVEF and clinical characteristics and in-hospital management in the "real world." METHODS Registries including the(More)
The early diagnosis of acute coronary syndrome (ACS) remains challenging, and a considerable proportion of patients are diagnosed with "possible" ACS on admission. The Global Registry of Acute Coronary Events (GRACE/GRACE(2)) and Canadian Registry of Acute Coronary Events (CANRACE) enrolled 16,618 Canadian patients with suspected ACS in 1999 to 2008. We(More)