François Blouin

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We report the results of an extensive computer search for good multiple recursive generators, in terms of their lattice structure and implementation speed. Those generators are a little slower than the usual linear congruential generators, but have much longer periods and much better statistical properties. We provide specific parameter sets for 32-bit,(More)
OBJECTIVE This study aims to evaluate the effects of intravaginal dehydroepiandrosterone (DHEA, prasterone) on the endometrium in postmenopausal women. METHODS Intravaginal DHEA (6.5 mg) was administered daily for 52 weeks to 422 women who had endometrial biopsy at baseline and end of study, whereas 15 women were similarly treated for 26 to 52 weeks.(More)
We present a class of random number generators defined by a linear congruential recursion of order <italic>k</italic> &#8805; 1, modulo <italic>m</italic>, and whose period can attain <italic>m</italic><supscrpt><italic>k</italic></supscrpt> - 1. The spectral test can be extended to this class of generators, and permits the computation of the distance(More)
OBJECTIVE An objective was to analyze the time course of efficacy of daily intravaginal administration of 0.5% (6.5mg) DHEA (prasterone) for 52 weeks on the moderate to severe (MS) symptoms and signs of vulvovaginal atrophy (VVA). METHOD Five hundred twenty-one postmenopausal women were enrolled and received daily intravaginal administration of 0.5% DHEA(More)
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