Floris Roelofsen

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PURPOSE To investigate the potential gain of the concomitant use of radiotherapy and chemotherapy in improving local control and reducing the need for colostomy, a randomized phase III trial was performed in patients with locally advanced anal cancer. MATERIALS AND METHODS From 1987 to 1994, 110 patients were randomized between radiotherapy alone and a(More)
This paper starts with an informal introduction to inquisitive semantics. After that, we present a formal definition of the semantics, and introduce the basic semantic notions of inquisitiveness and informativeness, in terms of wich we define the semantic categories of questions, assertions, and hybrid sentences. The focus of this paper will be on the(More)
In this paper we introduce a multi-context variant of Reiter’s default logic. The logic provides a syntactical counterpart of Roelofsen and Serafini’s information chain approach (IJCAI-05), yet has several advantages: it is closer to standard ways of representing nonmonotonic inference and a number of results from that area come “for free”; it is closer to(More)
The European Organization for Research and Treatment of Cancer (EORTC) 22861 randomised trial established that combined radiochemotherapy is the standard treatment for locally advanced anal cancer. This EORTC phase II study (#22953) tests the feasibility of reducing the gap between sequences to 2 weeks, to deliver Mitomycin C (MMC) in each radiotherapy(More)