Florie Bertrand

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BACKGROUND New models continue to be required to improve our understanding of colorectal cancer progression. To this aim, we characterised in this study a three-dimensional multicellular tumour model that we named colospheres, directly obtained from mechanically dissociated colonic primary tumours and correlated with metastatic potential. METHODS(More)
Most studies about social play have focused on its function in aiding socialization. It is not known whether play patterns vary by species according to specific adult social relationships. To test whether there is covariation between the form of play interactions and adult relationships, we studied social play in Japanese macaques (Macaca fuscata) and(More)
Through binding to and activation of two receptors, TNF-R1 and TNF-R2, Tumor Necrosis Factor α (TNF) modulates various biological processes in the immune system. A growing body of evidence in the literature indicates that TNF may behave as a tumorigenic cytokine, facilitating cancer cell immune escape and tumor progression. We have recently provided(More)
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