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The understanding of the processes underlying organellar function and inheritance requires the identification and characterization of the molecular components involved. We pursued a genomic approach to define the complements of genes required for respiratory growth and inheritance of mitochondria with normal morphology in yeast. With the systematic(More)
BACKGROUND The prognosis of metastatic non-small cell lung cancer (NSCLC) is still poor. Activating epithelial growth factor receptor (EGFR) mutations are important genetic alterations with dramatic therapeutical implications. Up to now, in contrast to Asian populations only limited data on the prevalence of those mutations are available from patients with(More)
We consider strictly stationary infinitely divisible processes and first extend the mixing conditions given in Maruyama [18] and Rosi´nski and ˙ Zak [23] from the univariate to the d-dimensional case. Thereafter, we show that multivariate Lévy-driven mixed moving average processes satisfy these conditions and hence a wide range of well-known processes such(More)
SUMMARY EBImage provides general purpose functionality for reading, writing, processing and analysis of images. Furthermore, in the context of microscopy-based cellular assays, EBImage offers tools to segment cells and extract quantitative cellular descriptors. This allows the automation of such tasks using the R programming language and use of existing(More)
Genetic screens for phenotypic similarity have made key contributions to associating genes with biological processes. With RNA interference (RNAi), highly parallel phenotyping of loss-of-function effects in cells has become feasible. One of the current challenges however is the computational categorization of visual phenotypes and the prediction of(More)
BACKGROUND In Drosophila, the early secretory apparatus comprises discrete paired Golgi stacks in close proximity to exit sites from the endoplasmic reticulum (tER sites), thus forming tER-Golgi units. Although many components involved in secretion have been identified, the structural components sustaining its organisation are less known. Here we set out to(More)
In a exible manufacturing environment a group of autonomous agents such as autonomous mobile robots and intelligent manufacturing units is supposed to cooperate and avoid bad interaction. Thus they must have the capability to build a common multi-agent plan through detailed adequate agreements and take into consideration the group goals as well as those of(More)
With the increasing amount of digital multimedia content, the user is more and more overstrained. A promising solution for this problem is personalization that assists the user in selecting content with respect to the user's interest. Since the capabilities of mobile devices increased significantly in the recent years, the number of <i>mobile</i> multimedia(More)