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OBJECTIVE Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and is associated with an enhanced risk for liver and cardiovascular diseases and mortality. NAFLD can progress from simple hepatic steatosis to non-alcoholic steatohepatitis (NASH). However, the mechanisms predisposing to this progression remain undefined. Notably,(More)
Today, in more and more enterprises digital services are offered to employees. An inherent characteristic of digital service is the self-service concept. Based on findings from a case study and academic literature, it is argued for the importance of employee knowledge when designing digital services. It is revealed that existing service blueprinting(More)
BACKGROUND Ulcerative colitis (UC) is a chronic inflammatory disorder of still unknown pathogenesis. Increasing evidence indicates that alterations in mitochondrial respiration and thus adenosine triphosphate (ATP) production are involved. This may contribute to mucosal energy deficiency and subsequently intestinal barrier malfunction, which is accepted to(More)
Configuration-Management-Databases (CMDBs) stellen einen zentralen Speicher für die Verwaltung aller Informationen und Beziehungen in IT-Infrastrukturen dar. Sie dienen Unternehmen für die Entscheidungsunterstützung. Aufgrund ihrer Graph-orientierten Grundstruktur liegt ihre Implementierung auf Basis von modernen Graph-Datenbankensystemen nahe. Deren(More)