• Publications
  • Influence
Identification of a cellular ligand for the natural cytotoxicity receptor NKp44.
With an array of activating and inhibitory receptors, natural killer (NK) cells are involved in the eradication of infected, transformed, and tumor cells. NKp44 is a member of the naturalExpand
  • 140
  • 20
Membrane-bound and soluble IL-15/IL-15Ralpha complexes display differential signaling and functions on human hematopoietic progenitors.
Membrane-bound and soluble interleukin-15 (IL-15)/IL-15 receptor alpha (Ralpha) complexes trigger differential transcription factor activation and functions on human hematopoietic progenitors.Expand
  • 65
  • 2
NKp44L expression on CD4+ T cells is associated with impaired immunological recovery in HIV-infected patients under highly active antiretroviral therapy
Objective:HIV-infected immunological nonresponders (InRs) patients fail to show satisfactory CD4+ T-cell recovery despite virologically effective HAART. We propose that NKp44L, the cellular ligand ofExpand
  • 18
  • 1
A Polysaccharide Virulence Factor of a Human Fungal Pathogen Induces Neutrophil Apoptosis via NK Cells
Aspergillus fumigatus is an opportunistic human fungal pathogen that sheds galactosaminogalactan (GG) into the environment. Polymorphonuclear neutrophils (PMNs) and NK cells are both part of theExpand
  • 42
  • PDF
Expansion of CMV-Mediated NKG2C+ NK Cells Associates with the Development of Specific De Novo Malignancies in Liver-Transplanted Patients
Solid cancers are a major adverse outcome of orthotopic liver transplantation (OLT). Although the use of chronic immunosuppression is known to play a role in T cell impairment, recent insights intoExpand
  • 17
  • PDF
Constitutive expression of ligand for natural killer cell NKp44 receptor (NKp44L) by normal human articular chondrocytes.
Normal chondrocytes display susceptibility to lysis by natural killer (NK) cells and this phenomenon may play a role in some inflammatory cartilage disorders. The mechanisms of chondrocyteExpand
  • 16
The Modulation of the Cell-Cycle: A Sentinel to Alert the NK Cells of Dangers
Natural killer (NK) cells are an essential component of innate immunity that provides a rapid response to detect stressed, infected, or transformed target cells. This system is controlled by aExpand
  • 12
  • PDF
IMMUNOBIOLOGY Identi fi cation of a cellular ligand for the natural cytotoxicity receptor NKp 44
Natural killer (NK) cells are critical components of the innate immune response, comprising the first line of defense against a variety of tumors and microbial pathogens before any sensitization. AnExpand
  • 3
  • PDF
Natural killer cell deficiency in patients with non-Hodgkin lymphoma after lung transplantation.
BACKGROUND Post-transplant non-Hodgkin lymphoma (NHL) is a well-recognized complication of solid-organ transplantation, and pharmacologic suppression of adaptive immunity plays a major role in itsExpand
  • 5
Transplantation-induced cancers
Solid cancers are a major adverse outcome of liver transplantation. Recent reassessments have revealed insights into causal factors, primarily centering on modulations of the natural killer (NK) cellExpand
  • 2