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- M Genini, P. -V. Schwalbe, Florence A. Scholl, Andrew Remppis, Marie Geneviève Mattei, Beat W. Schäfer
- DNA and cell biology
- 1997
A subtractive cloning procedure was used to characterize the molecular changes involved in transformation of normal myoblasts to rhabdomyosarcoma (RMS) cells. Here we describe the cloning of DRAL, a… (More)
- Ramon Wicki, Clemens Franz, Florence A. Scholl, Claus Wilhelm Heizmann, Beat W. Schäfer
- Cell calcium
- 1997
The calcium-binding protein S100A2 is expressed in normal breast tissue but downregulated during breast cancer progression. Hence it was previously identified as a candidate tumor suppressor gene. In… (More)
- Florence A. Scholl, Phillip A. Dumesic, +4 authors Paul A. Khavari
- Developmental cell
- 2007
The p42/p44 mitogen-activated protein kinase (MAPK) cascade includes Ras, Raf, Mek, and Erk MAPK. To determine the effect of a full knockout at a single level of this signaling pathway in mammals,… (More)
- Florence A. Scholl, Jivko Kamarashev, Omar V. Murmann, Ralf Geertsen, Reinhard Dummer, Beat W. Schäfer
- Cancer research
- 2001
Deregulated expression of the transcription factor PAX3 was observed previously in several tumors like rhabdomyosarcoma and Ewing's sarcoma. Because PAX3 expression is also found in pluripotent… (More)
- Phillip A. Dumesic, Florence A. Scholl, Deborah Isabel Barragan, Paul A. Khavari
- The Journal of cell biology
- 2009
Erk1/2 mitogen-activated protein kinases (MAPKs) are often hyperactivated in human cancers, where they affect multiple processes, including proliferation. However, the effects of Erk1/2 loss in… (More)
- Florence A. Scholl, Patricia McLoughlin, Elisabeth Ehler, Carla de Giovanni, Beat W. Schäfer
- The Journal of cell biology
- 2000
DRAL is a four and a half LIM domain protein identified because of its differential expression between normal human myoblasts and the malignant counterparts, rhabdomyosarcoma cells. In the current… (More)
- Bashar Saad, Karl Frei, Florence A. Scholl, Adriano Fontana, Patrick Maier
- European journal of biochemistry
- 1995
The regulation of acute-phase protein production and nitric oxide (NO) release in lipopolysaccharide-induced liver injury is thought to occur in response to monocytes/macrophages and… (More)
- M Genini, P. -V. Schwalbe, Florence A. Scholl, Beat W. Schäfer
- International journal of cancer
- 1996
Using a subtractive hybridization method, we have cloned 48 cDNAs which are expressed in human primary myoblasts but down-regulated in the embryonal-rhabdomyosarcoma (RMS) cell line RD. Twenty-nine… (More)
- Jason A. Reuter, Susana M. Ortiz-Urda, +6 authors Paul A. Khavari
- Cancer cell
- 2009
To elucidate mechanisms of cancer progression, we generated inducible human neoplasia in three-dimensionally intact epithelial tissue. Gene expression profiling of both epithelia and stroma at… (More)
- Florence A. Scholl, Phillip A. Dumesic, Paul A. Khavari
- Cancer letters
- 2005
Cell transformation is often a result of constitutive activation of genes in signaling pathways that regulate cell proliferation and differentiation. Indeed, the Ras/Raf/MEK/ERK mitogen-activated… (More)