Flora Banuett

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Two loci (the incompatibility or mating type loci), a and b, govern the life cycle of Ustilago maydis, a fungal pathogen of corn. U. maydis diploids heterozygous at both a and b (a[unk] b[unk]) form mycelial colonies (Fuz(+) phenotype), induce tumors, and produce teliospores able to undergo meiosis. We report here the isolation and characterization of(More)
Ustilago maydis is a ubiquitous pathogen of maize and a well-established model organism for the study of plant-microbe interactions. This basidiomycete fungus does not use aggressive virulence strategies to kill its host. U. maydis belongs to the group of biotrophic parasites (the smuts) that depend on living tissue for proliferation and development. Here(More)
Ustilago maydis induces tumors in maize. It is dimorphic, with a unicellular, nonpathogenic form, and a dikaryotic, filamentous, pathogenic form that requires the plant for its growth. The life cycle is regulated by two mating type loci, a and b: a has two alleles, which encode a pheromone and a receptor; b is multiallelic and encodes a combinatorial(More)
Recent studies of the corn smut fungus life cycle and its regulation by two mating type loci and other genes provide a cornucopia of challenges in cell biology, genetics and protein structure. The fungus can exist in two states: nonpathogenic and pathogenic. The change from one state to the other is accompanied by a change in morphology (yeast-like to(More)
U. maydis is a fungal pathogen of corn with two forms: one is yeast-like and nonpathogenic; the other is filamentous and pathogenic. The b locus, with 25 different alleles, regulates this dimorphism: any combination of two different alleles triggers pathogenic development, whereas the presence of identical alleles results in the yeast-like form. We have(More)
  • Flora Banuett
  • Microbiology and molecular biology reviews : MMBR
  • 1998
All cells, from bacteria and yeasts to mammalian cells, respond to cues from their environment. A variety of mechanisms exist for the transduction of these external signals to the interior of the cell, resulting in altered patterns of protein activity. Eukaryotic cells commonly transduce external cues via a conserved module composed of three protein(More)
Ustilago maydis is a plant pathogenic Basidiomycete fungus that exhibits dimorphism--it has a haploid, yeast-like phase and a dikaryotic, filamentous phase that is pathogenic. Establishment and maintenance of these two forms are controlled by two mating type loci, a and b. The a locus is thought to govern fusion of haploid cells to form a dikaryon and is(More)
Ustilago maydis is a dimorphic fungus with a yeast-like non-pathogenic form and a filamentous (hyphal) pathogenic form that induces tumor formation in maize. Within mature tumors, hyphae give rise to teliospores, which are round, diploid cells surrounded by a specialized cell wall. Here we describe the time course of fungal development in the plant with a(More)
Ustilago maydis is a dimorphic Basidiomycete fungus with a yeast-like form and a hyphal form. Here we present a comprehensive analysis of bud formation and the actin and microtubule cytoskeletons of the yeast-like form during the cell cycle. We show that bud morphogenesis entails a series of shape changes, initially a tubular or conical structure,(More)
  • Flora Banuett
  • Proceedings of the National Academy of Sciences…
  • 1991
Two master regulatory loci, a and b, govern life-cycle transitions of the phytopathogenic fungus Ustilago maydis. Fusion of haploids that differ at both a and b results in production of a filamentous dikaryon, which induces tumors in its host, maize. Here I describe identification of genes distinct from a and b that play roles in these life-cycle(More)