Flavien Léger

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This paper considers the multidimensional active scalar problem of motion of a function ρ(x, t) by a velocity field obtained by v = −∇N * ρ, where N is the Newtonian potential. We prove well-posedness of compactly supported L ∞ ∩ L 1 solutions of possibly mixed sign. These solutions include an important class of solutions that are proportional to(More)
A general framework based on Gaussian models and a MAPEM algorithm is introduced in this paper for solving matrix/ table completion problems. The numerical experiments with the standard and challenging movie ratings data show that the proposed approach, based on probably one of the simplest probabilistic models, leads to the results in the same ballpark as(More)
The aim of this study was to characterise the pharmacokinetics of the anticancer agent topotecan, and explore the influence of patient covariates and interoccasion variability on drug disposition. Data were obtained from 190 patients who received the drug as a 30-min infusion (N=72) or orally (N=118). The population model was built with the use of NONMEM to(More)
Received (Day Month Year) Revised (Day Month Year) Communicated by (xxxxxxxxxx) This paper considers the multidimensional active scalar problem of motion of a function ρ(x, t) by a velocity field obtained by v = −∇N * ρ, where N is the Newtonian potential. We prove well-posedness of compactly supported L ∞ ∩ L 1 solutions of possibly mixed sign. These(More)
24 This paper considers the multidimensional active scalar problem of motion of a function 25 ρ(x, t) by a velocity field obtained by v = −∇N * ρ, where N is the Newtonian potential. 26 We prove well-posedness of compactly supported L ∞ ∩ L 1 solutions of possibly mixed 27 sign. These solutions include an important class of solutions that are proportional(More)
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