Flávia Escremim de Paula

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Chronic tonsillar diseases are an important health problem, leading to large numbers of surgical procedures worldwide. Little is known about pathogenesis of these diseases. In order to investigate the role of respiratory viruses in chronic adenotonsillar diseases, we developed a cross-sectional study to determine the rates of viral detections of common(More)
The epidermal growth factor receptor (EGFR) is a member of the HER family of growth factors that activates several intracellular signaling pathways promoting proliferation and survival. EGFR over-expression is frequently associated with gene mutation or amplification, thereby constituting a major target for molecular therapies. Recently, a new generation of(More)
Alzheimer’s disease (AD) is a complex neurodegenerative disorder and the primary cause of dementia in the elderly and causes a decrease in cognition, functionality, and behaviour. Genetic risk factors play an important role in the pathogenesis of AD. In this case–control study, we aimed to investigate whether single nucleotide polymorphisms in MTHFR(More)
Oropouche virus (OROV) is an important cause of arboviral illness in Brazil and other Latin American countries, with most cases clinically manifested as acute febrile illness referred to as Oropouche fever, including myalgia, headache, arthralgia and malaise. However, OROV can also affect the central nervous system (CNS) with clinical neurological(More)
Purpose To evaluate the frequency of ARI and IL in JIA patients and its impact on disease activity, and to assess immu-nogenicity, safety and effectiveness of Flu vaccine in JIA patients using immunosuppressive drugs, including anti-TNFa. Methods Surveillance for Flu and other respiratory virus: respiratory syncytial virus (RSV), metapneumovirus (MPV),(More)
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