Flávia Dias Xavier

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We report our experience in 4 patients with chronic myeloid leukemia (CML) who had discontinued imatinib as a result of adverse events and had switched to dasatinib. The chronic phase (n 2) and accelerated phase (n 2) CML patients received dasatinib at starting dose of 100 and 140 mg once daily, respectively. Reappearance of hematological toxicity was(More)
While chronic lymphocytic leukemia (CLL) and chronic myeloid leukemia (CML) are common diseases in the elderly, they rarely occur simultaneously in the same patient. Here we present the case of a 77-year-old patient diagnosed with CML in the chronic phase who showed an optimal response to 400 mg/day of imatinib. This patient progressed to Binet B-CLL with(More)
  • F. Xavier
  • 2004
The oviduct of Nectophrynoides occidentalis Angel, a small viviparous toad of West Africa, is divided into four parts: ostium, tube, uterus and the distal common uterine segment. Only the ostium does not show seasonal variations: it always remains transparent and is devoid of glandular cells. A ciliated epithelium lines its lumen. The tube is rectilinear,(More)
A case of a follicular lymphoma transformed into a CD20(+) is described which progressed with the loss of CD20 expression after 8 cycles of R-CHOP. This phenomenon is not a rare event and has shown poor prognosis. Our purposes are to describe this event and suggest biopsy in relapsed or progressive disease.
Splenic blood-volume changes to norepinephrine were determined in the anesthetized cat by recording the integral of the difference between splenic arterial flow and splenic venous flow (flow-differential technique) with ultrasonic transit-time flowmeters, and the changes recorded with this technique were compared with those recorded with an independent(More)
BACKGROUND Venous thromboembolic events (VTEs) are common and potentially fatal complications in cancer patients, and they are responsible for the second most common cause of death. Low molecular weight heparin (LMWH) is the gold-standard treatment, but the costs involved limit its use, especially in developing countries. Recently, the oral anticoagulant(More)
OBJECTIVE Diffuse large B-cell lymphoma is the most common type of non-Hodgkin lymphoma, accounting for nearly 50% of the cases in the Hematology Department of the Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo and Instituto do Câncer do Estado de São Paulo. The treatment outcome is influenced by age, abnormal lactate(More)
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