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Continuous Distributed Representation of Biological Sequences for Deep Proteomics and Genomics

• Ehsaneddin Asgari, Mohammad R. K. Mofrad, Firas H. Kobeissy
• PloS one
• 2015

We introduce a new representation and feature extraction method for biological sequences. Named bio-vectors (BioVec) to refer to biological sequences in general with protein-vectors (ProtVec) for… (More)

Novel differential neuroproteomics analysis of traumatic brain injury in rats.

• Firas H. Kobeissy, A. K. Ottens, +6 authors Kevin K W Wang
• Molecular & cellular proteomics : MCP
• 2006

Approximately two million traumatic brain injury (TBI) incidents occur annually in the United States, yet there are no specific therapeutic treatments. The absence of brain injury diagnostic… (More)

Calpain-mediated collapsin response mediator protein-1, -2, and -4 proteolysis after neurotoxic and traumatic brain injury.

• Zhiqun Zhang, A. K. Ottens, +4 authors Kevin K. W. Wang
• Journal of neurotrauma
• 2007

Collapsin response mediator proteins (CRMPs) are important molecules in neurite outgrowth and axonal guidance. Within the CRMP family, CRMP-2 has been implicated in several neurological diseases… (More)

Direct Rho-associated kinase inhibiton induces cofilin dephosphorylation and neurite outgrowth in PC-12 cells

• Zhiqun Zhang, A. K. Ottens, +4 authors Kevin K. W. Wang
• Cellular & Molecular Biology Letters
• 2006

Axons fail to regenerate in the adult central nervous system (CNS) following injury. Developing strategies to promote axonal regeneration is therapeutically attractive for various CNS pathologies… (More)

Performance enhancing, non-prescription use of Ritalin: a comparison with amphetamines and cocaine.

• Stanislay I Svetlov, Firas H. Kobeissy, MarkS. Gold
• Journal of addictive diseases
• 2007

Ritalin, known under chemical name methylphenidate (MPH), is a psychostimulant prescribed to treat attention-deficit/hyperactivity disorder (ADHD) and other conditions. Psychotropic effects and… (More)

Food addiction and obesity: evidence from bench to bedside.

• Yijun Liu, Karen M. Von Deneen, Firas H. Kobeissy, MarkS. Gold
• Journal of psychoactive drugs
• 2010

Obesity has become a major health problem and epidemic. However, much of the current debate has been fractious and etiologies of obesity have been attributed to eating behavior or fast food,… (More)

CSF and Plasma Amyloid-β Temporal Profiles and Relationships with Neurological Status and Mortality after Severe Traumatic Brain Injury

• Stefania Mondello, Andràs Buki, +6 authors Andreas Jeromin
• Scientific reports
• 2014

The role of amyloid-β (Aβ) neuropathology and its significant changes in biofluids after traumatic brain injury (TBI) is still debated. We used ultrasensitive digital ELISA approach to assess… (More)

Molecular Consequences of Proprotein Convertase 1/3 (PC1/3) Inhibition in Macrophages for Application to Cancer Immunotherapy: A Proteomic Study.

• Marie Duhamel, Franck Rodet, +10 authors Michel Salzet
• Molecular & cellular proteomics : MCP
• 2015

Macrophages provide the first line of host immune defense. Their activation triggers the secretion of pro-inflammatory cytokines and chemokines recruiting other immune cells. In cancer, macrophages… (More)

Preadolescent tobacco smoke exposure leads to acute nicotine dependence but does not affect the rewarding effects of nicotine or nicotine withdrawal in adulthood in rats

• Hidetaka Yamada, Mahendra Bishnoi, +8 authors Adrie W. Bruijnzeel
• Pharmacology Biochemistry and Behavior
• 2010

Epidemiological studies indicate that parental smoking increases the risk for smoking in children. However, the underlying mechanisms by which parental smoking increases the risk for smoking are not… (More)

Proteomic Analysis of the Spatio-temporal Based Molecular Kinetics of Acute Spinal Cord Injury Identifies a Time- and Segment-specific Window for Effective Tissue Repair.

• Stéphanie Devaux, Dasa Cizkova, +14 authors Michel Salzet
• Molecular & cellular proteomics : MCP
• 2016

Spinal cord injury (SCI) represents a major debilitating health issue with a direct socioeconomic burden on the public and private sectors worldwide. Although several studies have been conducted to… (More)

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