Fiona Sutherland

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Omega-3 polyunsaturated fatty acids in fish oils may have antifibrillatory effects; however, their electrophysiologic effects in paroxysmal atrial fibrillation (PAF) remain unknown. The aim of this study was to investigate the effects of chronic fish oil supplementation on human pulmonary vein (PV) and left atrial electrophysiology in PAF. Patients with PAF(More)
BACKGROUND Persistent atrial fibrillation (AF) is associated with a high risk of recurrence after electrical cardioversion. OBJECTIVE We examined if long-term supplementation with omega-3 polyunsaturated fatty acids in fish oils commenced >1 month prior to electrical cardioversion and continued thereafter reduces recurrence of persistent AF. METHODS(More)
BACKGROUND Omega-3 polyunsaturated fatty acids in fish oils may have antifibrillatory effects. Their mechanism of action in humans is poorly understood. OBJECTIVE The purpose of this study was to investigate the effects of chronic fish oil supplementation on human atrial electrophysiology (EP). METHODS Two groups of patients without clinical AF or(More)
BACKGROUND Atrial mechanical stunning is a form of tachycardia-mediated atrial cardiomyopathy that manifests after reversion of persistent atrial arrhythmias to sinus rhythm. OBJECTIVES This study sought to examine whether chronic omega-3 polyunsaturated fatty acid supplementation with fish oils can reverse atrial mechanical stunning. METHODS Patients(More)
INTRODUCTION The transesophageal echo probe (TEE) is commonly used before and during atrial fibrillation (AF) ablation under general anesthesia (GA). We sought to determine the potential contribution of the TEE probe to esophageal injury after pulmonary vein isolation (PVI) alone for paroxysmal AF. METHODS AND RESULTS Seventy-six patients undergoing PVI(More)
BACKGROUND Intravenous omega-3 polyunsaturated fatty acids (ω-3 PUFAs) may prevent atrial fibrillation (AF) inducibility and perpetuation in animal models. We examined the effect of high dose IV ω-3 PUFAs on human atrial electrophysiology. METHODS AND RESULTS We randomised 88 patients with no structural heart disease to receive saline (control group) or(More)
BACKGROUND Complex fractionated atrial electrograms (CFAEs) are often identified as targets for radiofrequency ablation in the coronary sinus (CS) of patients with atrial fibrillation (AF). OBJECTIVE The purpose of this study was to determine whether similar features are present in a normal control population. METHODS Twenty-four patients with AF (12(More)
BACKGROUND Inducibility of atrial fibrillation (AF) after pulmonary vein isolation has been used to guide additional left atrial ablation in paroxysmal AF. The sensitivity and specificity of AF induction in this setting remains uncertain. We examined the incidence and characteristics of inducible AF in patients without structural heart disease or clinical(More)
BACKGROUND Sino-atrial node disease and aging increase AF risk. We investigated if long-term fish oil supplementation reduces paroxysmal atrial tachycardia/fibrillation (AT/AF) burden in patients aged ≥60 years with sinoatrial node disease and dual chamber pacemakers. METHODS Following a run-in period of 6 months (p1) where AT/AF burden was logged,78(More)
This research program examined the effectiveness of the Recovery is Possible for Everyone(RIPE) a community based transdiagnostic group treatment program for adults with eating disorders. Study 1 used retrospectively collected clinical data to evaluate the effectiveness of two versions of the RIPE program, the original CBT-based program and a more recent(More)
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