Fidias Eugenio León-Sarmiento

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Abnormal sensory processing seems to be involved in hyperhidrosis. To test this hypothesis, we investigated tactile acuity and cortical plastic changes in patients with primary hyperhidrosis (PH) and their asymptomatic relatives. We studied thirteen subjects belonging to two families with PH and thirteen age-matched healthy controls using Johnson-Van(More)
Single and paired-pulse transcranial magnetic stimulation (TMS) were applied to the motor cortex of 12 healthy volunteers, who were instructed to relax under eyes-open and eyes-closed conditions with room lights on and after 30 min of blindfolding. Compared to the eyes-open condition, significantly larger motor-evoked potentials and less intracortical(More)
OBJECTIVE To investigate cortical regions related to voluntary blinking. METHODS Transcranial magnetic stimulation (TMS) was applied to the facial motor cortex (M1) and the midline frontal region (Fz) in 10 healthy subjects with eyes opened and closed. Motor-evoked potentials were recorded from the orbicularis oculi (OOC), orbicularis oris (OOR), abductor(More)
A number of sensory changes occur in the earliest stages of Parkinson's disease (PD), some of which precede the expression of the classic motor phenotype by years (e.g., olfactory dysfunction). Whether point pressure sensitivity (PPS), a cutaneous measure of light touch mediated by myelinated Aβ fibers, is altered in early PD is not clear. Prior studies on(More)
OBJECTIVE To determine the prevalence of eight neurological problems-migraine, cerebrovascular disease, Parkinson's disease, peripheral neuropathy, disorders of neurological development, epilepsy, dementia, and sequelae of head trauma-in Colombia as a part of the National Neuroepidemiological Study (EPINEURO). METHODS A cross-sectional survey was carried(More)
In this study we demonstrate that myasthenia gravis, an autoimmune disease strongly identified with deficient acetylcholine receptor transmission at the post-synaptic neuromuscular junction, is accompanied by a profound loss of olfactory function. Twenty-seven MG patients, 27 matched healthy controls, and 11 patients with polymiositis, a disease with(More)
AIMS The aim of this study was to determine the prevalence of migraine and its implications in the occupational and outside employment/daily activities of the workers at a regional hospital in the Cundiboyacense Plateau in Colombia. PATIENTS AND METHODS The available members of the house staff at this institution were interviewed by applying the(More)
BACKGROUND AND AIMS The motor-evoked potential (MEP) induced by transcranial magnetic stimulation (TMS), its recruitment and the conditioning effects of weak stimuli in Parkinson's disease (PD) have shown contradictory results. The aim of this study is to definitively establish the influences of PD on the TMS-evoked MEP. METHODS We investigated resting(More)
OBJECTIVE To report a case of Pisa syndrome in a patient with idiopathic normal pressure hydrocephalus, who had never been exposed to psychotropic medications. METHODS A 26 years-old, Colombian, male patient, was referred because he had cognitive abnormalities, gait disturbances and urinary incontinence. This patient also displayed pleurothotonos.(More)
OBJECTIVE To determine the presence of eight neurological disorders (migraine, cerebrovascular disease, disorders of movement, peripheral neuropathy, mental retardation, epilepsy, dementia and the sequelas of head injuries) in the eastern region of Colombia. PATIENTS AND METHODS Using the neuro epidemiological protocol of the World Health Organization(More)