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This double-blind, randomized, placebo-controlled trial examined the effects of 4 wk of resting exposure to intermittent hypobaric hypoxia (IHE, 3 h/day, 5 days/wk at 4,000-5,500 m) or normoxia combined with training at sea level on performance and maximal oxygen transport in athletes. Twenty-three trained swimmers and runners completed duplicate baseline(More)
This study aimed to determine whether brief hypoxic stimuli in a hypobaric chamber are able to elicit erythropoietin (EPO) secretion, and to effectively stimulate erythropoiesis in the short term. In two different experiments, a set of haematological, biochemical, haemorheological, aerobic performance, and medical tests were performed in two groups of(More)
This study develops multivariate models to predict swimming performance based on multidimensional assessment. 66 male (age 13.6 +/- 0.6 y) and 67 female (11.5 +/- 0.6 y) swimmers undertook a test battery including a sports background and training questionnaire, anthropometry, general and specific fitness tests, and technique. Competitive performance (LEN(More)
This study tested the hypothesis that athletes exposed to 4 wk of intermittent hypobaric hypoxia exposure (3 h/day, 5 days/wk at 4,000-5,500 m) or double-blind placebo increase their red blood cell volume (RCV) and hemoglobin mass (Hbmass) secondary to an increase in erythropoietin (EPO). Twenty-three collegiate level athletes were measured before (Pre) and(More)
PURPOSE The purpose of the study was to examine the effect of a very short intermittent exposure to moderate hypoxia in a hypobaric chamber on aerobic performance capacity at sea level and the erythropoietic response. The effects of hypobaric hypoxia alone and combined with low-intensity exercise were also compared. METHODS Seventeen members of three(More)
The purpose of the present study is to detect by means of MRI any structural changes in the brain and their correlation with the clinical history of climbers who have ascended to extremely high altitudes without supplementary oxygen. Clinical history, neurological examinations and brain MRI were obtained from a group of 26 climbers who ascended to over 7000(More)
PURPOSE Humans can reduce inorganic nitrate (NO(3)(-)) to nitrite (NO(2)(-)), nitric oxide (NO), and other bioactive nitrogen oxides. The purpose of this study was to test the hypothesis that a single dose of inorganic nitrate before exercise might enhance the tolerance of endurance athletes to high intensity exercise. METHODS Eleven cyclists (age = 34.3(More)
BACKGROUND This study compared the cardiorespiratory response of trained swimmers to 400-m unimpeded front crawl swimming (SW), treadmill running (TR) and ergometer cycling (EC) maximal exercise tests, and evaluated the validity and specificity of a method to measure maximal aerobic power in swimming. METHODS Two series of experiments were conducted. In(More)
The effect of acute hypoxia on blood concentration of ammonia ([NH3]b) and lactate (la-]b) was studied during incremental exercise(IE), and two-step constant workload exercises (CE). Fourteen endurance-trained subjects performed incremental exercise on a cycle ergometer under normoxic (21% O2) and hypoxic (10.4% O2) conditions. Eight endurance-trained(More)
Studies that aim to characterize oxygen uptake kinetics in efforts above maximal oxygen consumption intensity are scarce. Our aim was to analyze the oxygen kinetics in a maximal 200-m front crawl, all measurements being conducted in swimming pool conditions. 10 high-level male swimmers performed a maximal 200-m bout and oxygen uptake was directly measured(More)