Fernando Suárez

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Actin-based stress fiber formation is coupled to microtubule depolymerization through the local activation of RhoA. While the RhoGEF Lfc has been implicated in this cytoskeleton coupling process, it has remained elusive how Lfc is recruited to microtubules and how microtubule recruitment moderates Lfc activity. Here, we demonstrate that the dynein light(More)
In this study, we introduce a novel approach to induce and observe the formation of presynaptic compartments in axons through a combination of atomic force microscopy (AFM) and fluorescence microscopy. First, we use a poly-D-lysine-coated bead attached to an AFM tip to induce the recruitment of two synaptic proteins, bassoon and synaptophysin, and measure(More)
Despite the fact that JSON is currently one of the most popular formats for exchanging data on the Web, there are very few studies on this topic and there are no agreement upon theoretical framework for dealing with JSON. Therefore in this paper we propose a formal data model for JSON documents and, based on the common features present in available systems(More)
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