Fernando Palos

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A simple, parametric model of the gradient refractive index distribution (GRIN) of the human lens with conicoid surfaces able to adapt to individual distributions as well as to the changes of the lens shape and structure with age and accommodation is presented. The first part of this work was published in a companion paper [J. Opt. Soc. Am. A24, 2175(More)
A simple, parametric adaptive model of the refractive index distribution of the ex vivo crystalline lens is presented. It assumes conicoid (or nonrevolution quadric in 3D) iso-indical surfaces, concentric with the external surfaces of the lens. The model uses a minimum number of internal structural parameters, while the shape of the iso-indical surfaces(More)
CONTEXT We studied two families from Galicia (northwest Spain) with Pendred syndrome (PS) and unusual thyroid phenotypes. In family A, the proposita had a large goiter and hypothyroxinemia but normal TSH and free T3 (FT3). In family B, some affected members showed deafness but not goiter. OBJECTIVE Our objective was to identify the mutations causing PS(More)
PURPOSE New designs of ophthalmic lenses customised for particular wearing conditions (e.g., vertex distance or wrap tilt angle) have emerged during the last few years. However, there is limited information about the extent of any improvement in visual quality of these products. The aim of this work was to determine whether customisation according to the(More)
PURPOSE To develop a realistic model of the optomechanical behavior of the cornea after curved relaxing incisions to simulate the induced astigmatic change and predict the optical aberrations produced by the incisions. SETTING ICMA Consejo Superior de Investigaciones Científicas and Universidad de Zaragoza, Zaragoza, Spain. METHODS A 3-dimensional(More)
Our main objective was to search for mutations in candidate genes and for paired box gene 8-peroxisome proliferator-activated receptor gamma (PAX8-PPARgamma) rearrangement in a well-differentiated angioinvasive follicular thyroid carcinoma (FTC) causing hyperthyroidism. DNA and RNA were extracted from the patient's thyroid tumor, as well as 'normal' thyroid(More)
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