Fernando García

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MicroRNAs (miRNAs) are noncoding RNAs that regulate expression of target mRNAs and are controlled by tumor suppressors and oncogenes. Altered expression of specific miRNAs in several tumor types and its association with poor prognosis parameters have been reported. Fewer data are available on its impact on patients' survival. We studied the impact of the(More)
BACKGROUND The ANSWER study aims to identify risk factors leading to increased cardiovascular morbidity and mortality in a Spanish incident haemodialysis population. This paper summarizes the baseline characteristics of this population. METHODS A prospective, observational, one-cohort study, including all consecutive incident haemodialysis patients from(More)
Intraneural hematoma after a peripheral nerve block is a theoretical cause of postoperative nerve injury that has not been previously documented in humans. We report an intraneural hematoma after nerve stimulation-guided femoral block, which occurred in a patient with undiagnosed factor XI deficiency and a slightly prolonged activated partial thromboplastin(More)
BACKGROUND Although the association between low haemoglobin levels and mortality is well established in haemodialysis patients, data are conflicting regarding levels >12 g/dl. In addition, divergent results have been reported on the relation between erythropoiesis-stimulating agents (ESAs) and mortality. METHODS This was a multicentre, observational,(More)
Stochastic models are widely used in some fields of Language Technology. Dialogue systems are one interesting application in Language Technology. In recent years, the stochastic modelling approach of dialogue systems has gained interest. These stochastic models are estimated from a set of annotated dialogues. The definition of the set of labels to annotate(More)
BACKGROUND The aim of the study was to compare three different apheresis machines with the same donors regarding the processing time required to obtain a 3.5 x 10(11) platelet (PLT) dose and acceptance by donors. STUDY DESIGN AND METHODS A randomized crossover trial was performed to evaluate the differences between the Amicus Crescendo (Baxter Biotech(More)
OBJECTIVE Evaluate the impact of switching from twice-daily zidovudine/lamivudine (AZT/3TC) to once-daily tenofovir DF plus emtricitabine (TDF/FTC) with efavirenz (EFV). DESIGN Prospective, multicenter, single-arm 24-week trial. METHODS Patients on EFV + AZT/3TC for > or =8 weeks with HIV-1 RNA <400 copies/mL were switched to EFV + TDF/FTC and assessed(More)
In this work, we present an approach to take advantage of confidence measures obtained during the recognition and understanding processes of a dialog system, in order to guide the behavior of the dialog manager. Our approach allows the system to ask the user for confirmation about the data which have low confidence values associated to them, after the(More)