Fernando Frutos

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CONTEXT The outcome of patients receiving mechanical ventilation for particular indications has been studied, but the outcome in a large number of unselected, heterogeneous patients has not been reported. OBJECTIVE To determine the survival of patients receiving mechanical ventilation and the relative importance of factors influencing survival. DESIGN,(More)
BACKGROUND Weaning patients from mechanical ventilation is an important problem in intensive care units. Weaning is usually conducted in an empirical manner, and a standardized approach has not been developed. METHODS We carried out a prospective, randomized, multicenter study involving 546 patients who had received mechanical ventilation for a mean (+/-(More)
To describe the incidence, risk factors, and impact on mortality of acute kidney injury (AKI) in patients with 2009 influenza A (H1N1) viral pneumonia requiring mechanical ventilation. Observational cohort study. AKI was defined as risk, injury or failure, according to the RIFLE classification. Early and late AKI were defined as AKI occurring on intensive(More)
We examined the effect on survival of prone positioning as an early and continuous treatment in ARDS patients already treated with protective ventilation. Open randomized controlled trial in 17 medical-surgical ICUs. Forty mechanically ventilated patients with early and refractory ARDS despite protective ventilation in the supine position. Patients were(More)
OBJECTIVE To evaluate the effects of increased oxygen delivery on mortality and morbidity. DESIGN Randomized, controlled trial. SETTING Medical-surgical ICU of a tertiary care hospital. PATIENTS Sixty-three patients classified according to predetermined criteria as having severe sepsis or septic shock. INTERVENTIONS The patients were randomly(More)
To describe the daily practice of mechanical ventilation (MV), and secondarily, its outcome in pediatric intensive care units (PICUs). Prospective cohort of infants and children who received MV for at least 12 h. Thirty-six medical surgical PICUs. All consecutive patients admitted to the PICUs during 2-month period. Of the 1893 patients admitted, 659 (35%)(More)
Use of mechanical ventilation has increased in recent years and constitutes a major therapeutic modality in the intensive care unit (ICU). In the recent years, changes in the ventilatory modes, in the ventilatory strategies and in the weaning from mechanical ventilation have occurred. We have compared the data obtained from the Spanish ICUs in studies that(More)
BACKGROUND Recent studies have found an association between increased volume and increased intensive care unit (ICU) survival; however, this association might not hold true in ICUs with permanent intensivist coverage. Our objective was to determine whether ICU volume correlates with survival in the Spanish healthcare system. METHODS Post hoc analysis of a(More)
OBJECTIVE To analyze the impact of decannulation before intensive care unit discharge on ward survival in nonexperimental conditions. DESIGN Prospective, observational survey. SETTING Thirty-one intensive care units throughout Spain. PATIENTS All patients admitted from March 1, 2008 to May 31, 2008. INTERVENTIONS None. MEASUREMENTS AND MAIN(More)
Introduction Extubation failure in critically ill patients has associated morbidity, but it cannot be safely predicted or avoided. Preventive NIMV has proved beneficial only in hypercapnic patients. We hypothesized that High-flow oxygen therapy may reduce postextubation respiratory failure due to gas humidification, avoidance of lung collapse by moderate(More)