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In order to take advantage of the significant benefits afforded by computational electromagnetic techniques, such as the finite-difference time-domain (FDTD) method, solvers capable of analyzing realistic problems in a reasonable time frame are required. Although software-based solvers are frequently used, they are often too slow to be of practical use. To(More)
OBJECTIVES To describe the effectiveness of the Surviving Sepsis Campaign bundles with regard to both implementation and outcome in patients with septic shock and to determine the contribution of the various elements of the bundles to the outcome. DESIGN Quasi-experimental study with a historical comparison group. SETTING The three medical-surgical(More)
Klotho gene codes for a protein with glucuronidase activity and is thought to influence bone and vascular homeostasis. We studied the relationship of a common T/G polymorphism, resulting in a phenylalanine (F) to valine (V) substitution at aminoacid position 352, with bone mineral density (BMD) and osteoporotic fractures. The study group comprised 914(More)
Early compliance with the sepsis resuscitation bundle has been suggested to reduce mortality. However, few data are available about the impact of late compliance with the bundle on outcomes. The aim of this study was to assess whether the completion of the resuscitation bundle within the first 6 h after admission to the intensive care unit (ICU), but beyond(More)
We reported previously that the expression of Wnt-related genes is lower in osteoporotic hip fractures than in osteoarthritis. We aimed to confirm those results by analyzing β-catenin levels and explored potential genetic and epigenetic mechanisms involved. β-Catenin gene expression and nuclear levels were analyzed by real time PCR and confocal(More)
Genotoxicity of three pesticides used in Costa Rican banana plantations. The in vitro genotoxic-ity of imazalil and thiabendazole fungicides and the insecticide chlorpyrifos, compounds used in Costa Rican banana plantations, was evaluated with the single-cell gel electrophoresis technique (comet assay). The comet assay is a simple, rapid and low cost(More)
The Electronic Government is a new field of applications for the semantic web where ontologies are becoming an important research technology. The e-Government faces considerable challenges to achieve interoperability given the semantic differences of interpretation, complexity and width of scope. In this paper we present the results obtained in an ongoing(More)
Designing nanoscale devices presents a number of unique challenges. As device features shrink, the computational demands of the simulations necessary to accurately model them increase significantly. This is a result of not only the increasing level of detail in the device design itself, but also the need to use more accurate models. The approximations that(More)
BACKGROUND Studies reporting the perspective of Latin American women, Ecuador, included, regarding the menopausal phenomena are scarce or lacking. OBJECTIVES Obtain information regarding the perception and attitudes toward the menopause among middle aged women of Guayaquil, Ecuador. METHODS Women aged 40 or more, nursing staff members of two major(More)