Fernando Afonso Santos

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Randomness is ubiquitous in nature. From single-molecule biochemical reactions to macroscale biological systems, stochasticity permeates individual interactions and often regulates emergent properties of the system. While such systems are regularly studied from a modeling viewpoint using stochastic simulation algorithms, numerous potential analytical tools(More)
We use a topological approach to describe the frustration- and field-induced phase transitions exhibited by the infinite-range XY model on the AB2 chain, including noncollinear spin structures. For this purpose, we have computed the Morse number and the Euler characteristic, as well as other topological invariants, which are found to behave similarly as a(More)
The requirements for quality of service (QoS) of applications in networks are becoming stricter. Toward to solve the routing problem in IP networks, MPLS architecture allows to define explicit routes in the network. This paper describes a multi-objective heuristic approach to solve the routing problem in MPLS networks. An evolutionary multi-objective(More)
OBJECTIVES To develop Portuguese evidence-based recommendations for pain management by pharmocotherapy in inflammatory arthritis. METHODS The Portuguese project was integrated in the multinational 3E Initiative (Evidence, Expertise, Exchange) 2010 where a total of 453 rheumatologists from 17 countries have participated. The clinical questions concerning(More)
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