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The Transcriptional Activator LdtR from ‘Candidatus Liberibacter asiaticus’ Mediates Osmotic Stress Tolerance

• Fernando A. Pagliai, Christopher L. Gardner, +7 authors Graciela L Lorca
• PLoS pathogens
• 2014

The causal agent of Huanglongbing disease, 'Candidatus Liberibacter asiaticus', is a non-culturable, gram negative, phloem-limited α-proteobacterium. Current methods to control the spread of this… (More)

LVIS553 transcriptional regulator specifically recognizes novobiocin as an effector molecule.

• Fernando A. Pagliai, Christopher L. Gardner, Santosh G Pande, Graciela L Lorca
• The Journal of biological chemistry
• 2010

In this study we aimed to identify small molecules with high affinity involved in the allosteric regulation of LVIS553, a MarR member from Lactobacillus brevis ATCC367. Using high throughput… (More)

The chemolithoautotroph Acidithiobacillus ferrooxidans can survive under phosphate-limiting conditions by expressing a C-P lyase operon that allows it to grow on phosphonates.

• Mário de Sá Vera, Fernando A. Pagliai, Nicolas Guiliani, C. Gonzalo Alvarez Jerez
• Applied and environmental microbiology
• 2008

The chemolithoautotrophic bacterium Acidithiobacillus ferrooxidans is of great importance in biomining operations. During the bioleaching of ores, microorganisms are subjected to a variety of… (More)

Inhibition of AcpA phosphatase activity with ascorbate attenuates Francisella tularensis intramacrophage survival.

• Steven McRae, Fernando A. Pagliai, +5 authors Claudio Feijóo González
• The Journal of biological chemistry
• 2010

Acid phosphatase activity in the highly infectious intracellular pathogen Francisella tularensis is directly related with the ability of these bacteria to survive inside host cells. Pharmacological… (More)

Identification of a Ligand Binding Pocket in LdtR from Liberibacter asiaticus

• Fernando A. Pagliai, Claudio Feijóo González, Graciela L Lorca
• Front. Microbiol.
• 2015

LdtR is a transcriptional activator involved in the regulation of a putative L,D transpeptidase in Liberibacter asiaticus, an unculturable pathogen and one of the causative agents of Huanglongbing… (More)

Drug Repurposing: Tolfenamic Acid Inactivates PrbP, a Transcriptional Accessory Protein in Liberibacter asiaticus

• Christopher L. Gardner, Fernando A. Pagliai, +4 authors Claudio Feijóo González
• Front. Microbiol.
• 2016

CLIBASIA_01510, PrbP, is a predicted RNA polymerase binding protein in Liberibacter asiaticus. PrbP was found to regulate expression of a small subset of ribosomal genes through interactions with the… (More)

Lactobacillus brevis responds to flavonoids through KaeR, a LysR-type of transcriptional regulator.

• Santosh G Pande, Fernando A. Pagliai, +4 authors Graciela L Lorca
• Molecular microbiology
• 2011

The ability of transcription factors to respond to flavonoids as signal molecules was investigated in Lactobacillus brevis. Through in vitro screening of a small library of flavonoids, LVIS1989… (More)

Functional Analysis of the Citrate Activator CitO from Enterococcus faecalis Implicates a Divalent Metal in Ligand Binding

• Víctor S. Blancato, Fernando A. Pagliai, Christian Magni, Claudio Feijóo González, Graciela L Lorca
• Front. Microbiol.
• 2016

The regulator of citrate metabolism, CitO, from Enterococcus faecalis belongs to the FCD family within the GntR superfamily. In the presence of citrate, CitO binds to cis-acting sequences located… (More)

Functional characterization of LotP from Liberibacter asiaticus

• Flavia del Valle Loto, Janelle F. Coyle, +4 authors Claudio Feijóo González
• Microbial biotechnology
• 2017

Liberibacter asiaticus is an unculturable parasitic bacterium of the alphaproteobacteria group hosted by both citrus plants and a psyllid insect vector (Diaphorina citri). In the citrus tree, the… (More)

A dual role of the transcriptional regulator TstR provides insights into cyanide detoxification in Lactobacillus brevis.

• Fernando A. Pagliai, Caitlin C Murdoch, Sara Melanie Brown, Claudio Feijóo González, Graciela L Lorca
• Molecular microbiology
• 2014

In this study we uncover two genes in Lactobacillus brevis ATCC 367, tstT and tstR, encoding for a rhodanese and a transcriptional regulator involved in cyanide detoxification. TstT (LVIS_0852)… (More)

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