Fernanda B Leitão

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The molecular mechanisms involved in Na+,K+-ATPase inhibition by 2-methoxy-3,8,9-trihydroxy coumestan were investigated. We show that this compound decreases the free sulfydryl groups present in the enzyme and that its inhibitory effect is prevented by dithiothreitol and other two sulfydryl containing reagents. We propose a redox cycle culminating with the(More)
The common failure of patients to follow medical instructions creates a problem for the physicians who need to know whether or not their patient are following advice. Lack of patient compliance with prescribed regimens is an important and fascinating problem in medical care. Reports indicate that patients do not follow medical instructions faithfully and(More)